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- W183060984 abstract "Publisher Summary This chapter focuses on the heart rate changes in neurogenic hypertension. Neurogenic hypertension has been produced in several mammalian species by radical denervation of the sino–aortic baroreceptor areas. In a study described in the chapter, when the heartbeats of the rat were measured by electrocardiography (ECG) through chronically implanted electrodes, the resting heart rate was quite low, that is, about 320 beats/minutes, indicating a predominance of the vagal tone. Total denervation of the sino–aortic areas produced a marked tachycardia reaching its maximum within 5 hours. Isolated denervation of the carotid and of the aortic fibers indicated that the aortic baroreceptors play a predominant role in heart rate regulation in the rat. Tachycardia progressively declined and the resting heart rate returned to normal in 10 days after total aortic denervation when the rats were still hypertensive. When the denervated rats were submitted to autonomie blockade with atropine and propranolol 3 days after recovering from tachycardia, their intrinsic heart rate was lower and their sympathetic and vagal tones smaller than for the rats with intact baroreceptors." @default.
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- W183060984 date "1981-01-01" @default.
- W183060984 modified "2023-09-25" @default.
- W183060984 title "HEART RATE CHANGES IN NEUROGENIC HYPERTENSION" @default.
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- W183060984 doi "https://doi.org/10.1016/b978-0-08-027348-8.50007-x" @default.
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