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• W1832002166 abstract "The expression of microRNA-31 (miR-31) has been implicated in the progression of some human malignancies including colorectal cancer. However, the clinical significance of the expression of miR-31 in submucosally invasive (T1) colorectal cancer remains unclear. The aim of the present study was to delineate the relationship between clinicopathological features and the oncogenic modulator miR-31 in submucosally invasive colorectal cancer. We investigated the expression of miR-31 in 50 submucosally invasive colorectal cancer specimens, along with the corresponding non-tumoral mucosa specimens, using a real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR). The relationships between miR-31 expression levels and clinicopathological characteristics were assessed. The miR-31 host gene locus was investigated using fluorescence in situ hybridization. qRT-PCR revealed that the expression of miR-31 was higher in colorectal cancer tissue than in non-tumoral tissue (P = 0.0002). The up-regulated expression of miR-31 may play an oncogenic role in the early stage of carcinogenesis in colorectal cancers." @default.
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• W1832002166 date "2015-07-15" @default.
• W1832002166 modified "2023-09-26" @default.
• W1832002166 title "The potential role of microRNA-31 expression in early colorectal cancer" @default.
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• W1832002166 doi "https://doi.org/10.1111/pin.12334" @default.
• W1832002166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26173758" @default.
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