Matches in SemOpenAlex for { <https://semopenalex.org/work/W1832237362> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1832237362 endingPage "247" @default.
- W1832237362 startingPage "247" @default.
- W1832237362 abstract "Blood monocytes from 45 selected patients with lung cancer and 30 healthy controls were incubated with [G-3H]-benzo(a)pyrene for 30 h, and the formation of covalently bound DNA adducts was determined. The lung cancer patients were either relatively young (below 46 yr), nonsmokers, or had at least one first degree relative with lung cancer. Therefore, they might be considered cancer prone. The DNA adducts were significantly elevated in 22 patients with early age cancer (4.34 fmol/micrograms of DNA; P less than 0.04). In 12 familial cases, the slight elevation (2.77 fmol/micrograms of DNA) was not statistically significant in comparison to healthy controls. Benzo(a)pyrene:DNA adduct levels did not differ significantly between smokers and nonsmokers. Eight of 9 lung cancer patients with DNA adducts equal or above 4.5 fmol/micrograms of DNA but only 16 of 36 with adducts below this value had either oat cell or squamous cell cancer (P less than 0.05). The observed enhanced formation of covalent DNA adducts in blood monocytes exposed to a carcinogenic polycyclic hydrocarbon may be genetically determined and could play a role in the development of lung cancer at an early age." @default.
- W1832237362 created "2016-06-24" @default.
- W1832237362 date "1986-12-01" @default.
- W1832237362 modified "2023-09-25" @default.
- W1832237362 title "Enhanced formation of benzo(a)pyrene: DNA adducts in monocytes of patients with a presumed predisposition to lung cancer" @default.
- W1832237362 cites W146578965 @default.
- W1832237362 cites W1511231895 @default.
- W1832237362 cites W1519556760 @default.
- W1832237362 cites W1555786273 @default.
- W1832237362 cites W1601039239 @default.
- W1832237362 cites W1881840670 @default.
- W1832237362 cites W1964294501 @default.
- W1832237362 cites W1973455044 @default.
- W1832237362 cites W1977863795 @default.
- W1832237362 cites W1978154354 @default.
- W1832237362 cites W1991233697 @default.
- W1832237362 cites W1994212278 @default.
- W1832237362 cites W1996114286 @default.
- W1832237362 cites W2002301710 @default.
- W1832237362 cites W2007190844 @default.
- W1832237362 cites W2023513664 @default.
- W1832237362 cites W2034581891 @default.
- W1832237362 cites W2039114288 @default.
- W1832237362 cites W2039638827 @default.
- W1832237362 cites W2046171723 @default.
- W1832237362 cites W2054815209 @default.
- W1832237362 cites W2070133223 @default.
- W1832237362 cites W2071287136 @default.
- W1832237362 cites W2078556790 @default.
- W1832237362 cites W2083652061 @default.
- W1832237362 cites W2086096842 @default.
- W1832237362 cites W2091061380 @default.
- W1832237362 cites W2102312152 @default.
- W1832237362 cites W2102726541 @default.
- W1832237362 cites W2111186399 @default.
- W1832237362 cites W2113022736 @default.
- W1832237362 cites W2148162464 @default.
- W1832237362 cites W2157437695 @default.
- W1832237362 cites W2289446848 @default.
- W1832237362 cites W607378709 @default.
- W1832237362 doi "https://doi.org/10.1016/s0169-5002(86)80684-5" @default.
- W1832237362 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4053059" @default.
- W1832237362 hasPublicationYear "1986" @default.
- W1832237362 type Work @default.
- W1832237362 sameAs 1832237362 @default.
- W1832237362 citedByCount "16" @default.
- W1832237362 crossrefType "journal-article" @default.
- W1832237362 hasConcept C108204754 @default.
- W1832237362 hasConcept C114246631 @default.
- W1832237362 hasConcept C121608353 @default.
- W1832237362 hasConcept C126322002 @default.
- W1832237362 hasConcept C134018914 @default.
- W1832237362 hasConcept C153911025 @default.
- W1832237362 hasConcept C178790620 @default.
- W1832237362 hasConcept C185592680 @default.
- W1832237362 hasConcept C2776256026 @default.
- W1832237362 hasConcept C2777538855 @default.
- W1832237362 hasConcept C2778951431 @default.
- W1832237362 hasConcept C552990157 @default.
- W1832237362 hasConcept C55493867 @default.
- W1832237362 hasConcept C71924100 @default.
- W1832237362 hasConcept C86803240 @default.
- W1832237362 hasConceptScore W1832237362C108204754 @default.
- W1832237362 hasConceptScore W1832237362C114246631 @default.
- W1832237362 hasConceptScore W1832237362C121608353 @default.
- W1832237362 hasConceptScore W1832237362C126322002 @default.
- W1832237362 hasConceptScore W1832237362C134018914 @default.
- W1832237362 hasConceptScore W1832237362C153911025 @default.
- W1832237362 hasConceptScore W1832237362C178790620 @default.
- W1832237362 hasConceptScore W1832237362C185592680 @default.
- W1832237362 hasConceptScore W1832237362C2776256026 @default.
- W1832237362 hasConceptScore W1832237362C2777538855 @default.
- W1832237362 hasConceptScore W1832237362C2778951431 @default.
- W1832237362 hasConceptScore W1832237362C552990157 @default.
- W1832237362 hasConceptScore W1832237362C55493867 @default.
- W1832237362 hasConceptScore W1832237362C71924100 @default.
- W1832237362 hasConceptScore W1832237362C86803240 @default.
- W1832237362 hasIssue "4" @default.
- W1832237362 hasLocation W18322373621 @default.
- W1832237362 hasLocation W18322373622 @default.
- W1832237362 hasOpenAccess W1832237362 @default.
- W1832237362 hasPrimaryLocation W18322373621 @default.
- W1832237362 hasRelatedWork W1516224401 @default.
- W1832237362 hasRelatedWork W1977543778 @default.
- W1832237362 hasRelatedWork W1997248328 @default.
- W1832237362 hasRelatedWork W1999975393 @default.
- W1832237362 hasRelatedWork W2055685382 @default.
- W1832237362 hasRelatedWork W2062202159 @default.
- W1832237362 hasRelatedWork W2079240507 @default.
- W1832237362 hasRelatedWork W2226624016 @default.
- W1832237362 hasRelatedWork W2414596920 @default.
- W1832237362 hasRelatedWork W4210695390 @default.
- W1832237362 hasVolume "2" @default.
- W1832237362 isParatext "false" @default.
- W1832237362 isRetracted "false" @default.
- W1832237362 magId "1832237362" @default.
- W1832237362 workType "article" @default.