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- W183227302 abstract "Membrane processes are increasingly reported for various applications in both upstream and downstream biotechnology. The advantages of membrane systems are their selectivity, high surface area per unit volume, and their potential for controlling the level of contact and/or mixing between two phases. Ultrafiltration and microfiltration are commonly used to concentrate proteins, exchange buffers, clarify suspensions for cell harvesting, and sterilize liquids to remove viruses and bacteria. Other membrane processes include membrane bioreactors, where enzymes, microorganisms, or antibodies are suspended in solution and compartmentalized by a membrane in a reaction vessel or immobilized within the membrane matrix itself. Membrane chromatography is used as an alternative to conventional resin-based chromatography columns, for a large range of chromatographic purification schemes, including ion-exchange, hydrophobic, reversed-phase, and affinity chromatography. Finally, membrane contactors involve the use of pressure to force the dispersed phase to permeate through a membrane into the continuous phase, for the preparation of emulsions and various types of particles. This article presents membrane processes by focusing on materials and devices; characterization; solute and particle deposition; membrane cleaning; and the large range of possible applications in the biotechnology field, such as ultrafiltration and microfiltration, membrane bioreactors, membrane chromatography, and membrane contactors." @default.
- W183227302 created "2016-06-24" @default.
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- W183227302 date "2011-01-01" @default.
- W183227302 modified "2023-10-16" @default.
- W183227302 title "Membrane Systems and Technology" @default.
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- W183227302 doi "https://doi.org/10.1016/b978-0-08-088504-9.00131-8" @default.
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