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• W1832483009 abstract "<b><i>Background:</i></b> Preeclampsia (PE) is relatively common and is unpredictable in its onset and progression. <b><i>Aims:</i></b> We investigated the clinical value of using the multiple of the median (MoM) of free β-human chorionic gonadotropin (β-hCG) concentrations in women with normal pregnancy and PE. <b><i>Methods:</i></b> This study was based on a dataset available from published studies, and the relevant studies were retrieved from multiple electronic databases. Data were extracted from case-control studies; a random-effects model was employed, and standardized mean difference and 95% confidence intervals were calculated. Twelve case-control studies (eleven English-based articles and one Chinese-based article) were analyzed in the current meta-analysis and included 702 patients with PE and 8,233 women with normal pregnancies. <b><i>Results:</i></b> Statistical analysis revealed a higher MoM of β-hCG serum levels in patients with PE. Ethnicity subgroup analysis showed that the MoM of serum β-hCG levels was significantly higher in women with PE in both Asian and Caucasian populations. <b><i>Conclusion:</i></b> The MoM of β-hCG serum levels was significantly increased in women with PE compared to women with normal pregnancies. Screening for serum β-hCG MoM levels will be helpful in the early identification of pregnancies at risk of developing PE." @default.
• W1832483009 created "2016-06-24" @default.
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• W1832483009 date "2015-08-26" @default.
• W1832483009 modified "2023-10-18" @default.
• W1832483009 title "Predictive Value of Free β-hCG Multiple of the Median for Women with Preeclampsia" @default.
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• W1832483009 doi "https://doi.org/10.1159/000433434" @default.
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