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- W1832774482 abstract "The authors report the development of a stimulation paradigm designed to induce the kindled state in a significantly shorter time frame than the traditional kindling model of epilepsy. This paradigm was used to examine kindling in prenatally protein malnourished adult rats. Electrical stimulations of 5-s duration were applied to the perforant pathway every 5 min for 1 h over 5 days. Behavioral manifestations of seizure were scored on a five-point scale. The rapid kindling paradigm described provides a means of examining the development of kindled seizures in a significantly shorter period of time, but with comparable behavioral and electrophysiological outcome, than the traditional kindling paradigm. >" @default.
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- W1832774482 date "2002-12-09" @default.
- W1832774482 modified "2023-09-25" @default.
- W1832774482 title "A rapid kindling paradigm used to examine hippocampal neuroplasticity" @default.
- W1832774482 cites W1978521090 @default.
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- W1832774482 doi "https://doi.org/10.1109/nebc.1991.154653" @default.
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