Matches in SemOpenAlex for { <https://semopenalex.org/work/W183302013> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W183302013 abstract "The hippocampus is one of the most vulnerable structures in the brain to ischemia. It is been widely believed that the hippocampus is most easily subject to neuronal death and “sclerosis” following only a brief period of ischemia of merely a few minutes. However, neurophysiologists have long been using the hippocampal slice method for their experiments. They know that their in vitro slice preparation of the hippocampus obtained mainly from rodent species is surprisingly normal and remains normal for many hours (Lynch, 1980). In this procedure, hippocampal tissue is unavoidably exposed to brief ischemia during preparation until it is cut into slices. The experience of neurophysiologists may, therefore, confirm that hippocampal neurons, if any, are only on rare occasions destroyed rapidly following brief ischemia. These seemingly contradictory observations may be resolved by the recognition of delayed neuronal death in the hippocampus. Most of the hippocampal CA1 neurons die following brief ischemia, but cell disintegration takes place very slowly (Kirino, 1982; Pulsinelli et al., 1982). It takes almost days until overt morphological signs of neuronal death appear. As the brain is subjected to longer ischemia, this neuronal cell alteration develops faster following recirculation (Kirino and Sano, 1984a). This general tendency of neuronal pathology is describled by Ito et al. and called “maturation phenomenon” (Ito et al., 1975). In the rodent hippocampus, delayed neuronal death is most commonly encountered in animals which survive longer than a few days following ischemia. On the other hand, ischemia which is long enough to cause widespread acute cell change in the hippocampus is usually incompatible with animal survival." @default.
- W183302013 created "2016-06-24" @default.
- W183302013 creator A5005634038 @default.
- W183302013 creator A5045601646 @default.
- W183302013 creator A5087772583 @default.
- W183302013 date "1988-01-01" @default.
- W183302013 modified "2023-09-25" @default.
- W183302013 title "Early and Late Neuronal Damage Following Cerebral Ischemia" @default.
- W183302013 cites W1982892406 @default.
- W183302013 cites W1983468192 @default.
- W183302013 cites W1983687430 @default.
- W183302013 cites W1996374240 @default.
- W183302013 cites W2006842487 @default.
- W183302013 cites W2019833059 @default.
- W183302013 cites W2020622209 @default.
- W183302013 cites W2023826599 @default.
- W183302013 cites W2024773521 @default.
- W183302013 cites W2035750459 @default.
- W183302013 cites W2041270165 @default.
- W183302013 cites W2045835005 @default.
- W183302013 cites W2063271495 @default.
- W183302013 cites W2067292092 @default.
- W183302013 cites W2072729793 @default.
- W183302013 cites W2072866840 @default.
- W183302013 cites W2086854267 @default.
- W183302013 cites W2140871341 @default.
- W183302013 cites W2141899399 @default.
- W183302013 cites W2404496781 @default.
- W183302013 doi "https://doi.org/10.1007/978-1-4684-5562-5_3" @default.
- W183302013 hasPublicationYear "1988" @default.
- W183302013 type Work @default.
- W183302013 sameAs 183302013 @default.
- W183302013 citedByCount "7" @default.
- W183302013 crossrefType "book-chapter" @default.
- W183302013 hasAuthorship W183302013A5005634038 @default.
- W183302013 hasAuthorship W183302013A5045601646 @default.
- W183302013 hasAuthorship W183302013A5087772583 @default.
- W183302013 hasConcept C126322002 @default.
- W183302013 hasConcept C148762608 @default.
- W183302013 hasConcept C169760540 @default.
- W183302013 hasConcept C190283241 @default.
- W183302013 hasConcept C2781161787 @default.
- W183302013 hasConcept C2993744773 @default.
- W183302013 hasConcept C31573885 @default.
- W183302013 hasConcept C541997718 @default.
- W183302013 hasConcept C55493867 @default.
- W183302013 hasConcept C71924100 @default.
- W183302013 hasConcept C86803240 @default.
- W183302013 hasConceptScore W183302013C126322002 @default.
- W183302013 hasConceptScore W183302013C148762608 @default.
- W183302013 hasConceptScore W183302013C169760540 @default.
- W183302013 hasConceptScore W183302013C190283241 @default.
- W183302013 hasConceptScore W183302013C2781161787 @default.
- W183302013 hasConceptScore W183302013C2993744773 @default.
- W183302013 hasConceptScore W183302013C31573885 @default.
- W183302013 hasConceptScore W183302013C541997718 @default.
- W183302013 hasConceptScore W183302013C55493867 @default.
- W183302013 hasConceptScore W183302013C71924100 @default.
- W183302013 hasConceptScore W183302013C86803240 @default.
- W183302013 hasLocation W1833020131 @default.
- W183302013 hasOpenAccess W183302013 @default.
- W183302013 hasPrimaryLocation W1833020131 @default.
- W183302013 hasRelatedWork W10676189 @default.
- W183302013 hasRelatedWork W111318761 @default.
- W183302013 hasRelatedWork W166976631 @default.
- W183302013 hasRelatedWork W1980322487 @default.
- W183302013 hasRelatedWork W2000051590 @default.
- W183302013 hasRelatedWork W2000542923 @default.
- W183302013 hasRelatedWork W2013723336 @default.
- W183302013 hasRelatedWork W2019970503 @default.
- W183302013 hasRelatedWork W2035750459 @default.
- W183302013 hasRelatedWork W2038418713 @default.
- W183302013 hasRelatedWork W2056250372 @default.
- W183302013 hasRelatedWork W2062432279 @default.
- W183302013 hasRelatedWork W2088750159 @default.
- W183302013 hasRelatedWork W209691036 @default.
- W183302013 hasRelatedWork W2113308503 @default.
- W183302013 hasRelatedWork W2133399305 @default.
- W183302013 hasRelatedWork W2160080880 @default.
- W183302013 hasRelatedWork W2384581857 @default.
- W183302013 hasRelatedWork W27062102 @default.
- W183302013 hasRelatedWork W8888957 @default.
- W183302013 isParatext "false" @default.
- W183302013 isRetracted "false" @default.
- W183302013 magId "183302013" @default.
- W183302013 workType "book-chapter" @default.