Matches in SemOpenAlex for { <https://semopenalex.org/work/W1833042232> ?p ?o ?g. }
- W1833042232 endingPage "963" @default.
- W1833042232 startingPage "953" @default.
- W1833042232 abstract "The dipeptide aspartame (Asp-Phe-OMe) is a sweetener widely used in replacement of sucrose by food industry. 2′,6′-Dimethyltyrosine (DMT) and 2′,6′-dimethylphenylalanine (DMP) are two synthetic phenylalanine-constrained analogues, with a limited freedom in χ-space due to the presence of methyl groups in position 2′,6′ of the aromatic ring. These residues have shown to increase the activity of opioid peptides, such as endomorphins improving the binding to the opioid receptors. In this work, DMT and DMP have been synthesized following a diketopiperazine-mediated route and the corresponding aspartame derivatives (Asp-DMT-OMe and Asp-DMP-OMe) have been evaluated in vivo and in silico for their activity as synthetic sweeteners." @default.
- W1833042232 created "2016-06-24" @default.
- W1833042232 creator A5016876491 @default.
- W1833042232 creator A5028615075 @default.
- W1833042232 creator A5040940946 @default.
- W1833042232 creator A5046245260 @default.
- W1833042232 creator A5053916797 @default.
- W1833042232 creator A5058021335 @default.
- W1833042232 creator A5068255593 @default.
- W1833042232 creator A5073853530 @default.
- W1833042232 date "2015-08-24" @default.
- W1833042232 modified "2023-09-25" @default.
- W1833042232 title "Exploring the biological consequences of conformational changes in aspartame models containing constrained analogues of phenylalanine" @default.
- W1833042232 cites W1757822092 @default.
- W1833042232 cites W1945680072 @default.
- W1833042232 cites W1965095422 @default.
- W1833042232 cites W1980701847 @default.
- W1833042232 cites W1986191025 @default.
- W1833042232 cites W1986689801 @default.
- W1833042232 cites W1999613945 @default.
- W1833042232 cites W2008517160 @default.
- W1833042232 cites W2009510905 @default.
- W1833042232 cites W2023571753 @default.
- W1833042232 cites W2030645331 @default.
- W1833042232 cites W2035266068 @default.
- W1833042232 cites W2038880710 @default.
- W1833042232 cites W2040482296 @default.
- W1833042232 cites W2041486926 @default.
- W1833042232 cites W2044172327 @default.
- W1833042232 cites W2045992598 @default.
- W1833042232 cites W2048457888 @default.
- W1833042232 cites W2055980566 @default.
- W1833042232 cites W2062292777 @default.
- W1833042232 cites W2062659400 @default.
- W1833042232 cites W2067174909 @default.
- W1833042232 cites W2071566170 @default.
- W1833042232 cites W2076790509 @default.
- W1833042232 cites W2077202970 @default.
- W1833042232 cites W2081693079 @default.
- W1833042232 cites W2109666390 @default.
- W1833042232 cites W2114367386 @default.
- W1833042232 cites W2126103175 @default.
- W1833042232 cites W2128332459 @default.
- W1833042232 cites W2128572087 @default.
- W1833042232 cites W2137015675 @default.
- W1833042232 cites W2140633386 @default.
- W1833042232 cites W2140703033 @default.
- W1833042232 cites W2141712000 @default.
- W1833042232 cites W2146256775 @default.
- W1833042232 cites W2152457327 @default.
- W1833042232 cites W2161960007 @default.
- W1833042232 cites W2162327153 @default.
- W1833042232 cites W2167191800 @default.
- W1833042232 cites W2171009743 @default.
- W1833042232 cites W2171268876 @default.
- W1833042232 cites W2325058109 @default.
- W1833042232 doi "https://doi.org/10.3109/14756366.2015.1076811" @default.
- W1833042232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26308194" @default.
- W1833042232 hasPublicationYear "2015" @default.
- W1833042232 type Work @default.
- W1833042232 sameAs 1833042232 @default.
- W1833042232 citedByCount "13" @default.
- W1833042232 countsByYear W18330422322017 @default.
- W1833042232 countsByYear W18330422322018 @default.
- W1833042232 countsByYear W18330422322019 @default.
- W1833042232 countsByYear W18330422322020 @default.
- W1833042232 countsByYear W18330422322021 @default.
- W1833042232 countsByYear W18330422322022 @default.
- W1833042232 crossrefType "journal-article" @default.
- W1833042232 hasAuthorship W1833042232A5016876491 @default.
- W1833042232 hasAuthorship W1833042232A5028615075 @default.
- W1833042232 hasAuthorship W1833042232A5040940946 @default.
- W1833042232 hasAuthorship W1833042232A5046245260 @default.
- W1833042232 hasAuthorship W1833042232A5053916797 @default.
- W1833042232 hasAuthorship W1833042232A5058021335 @default.
- W1833042232 hasAuthorship W1833042232A5068255593 @default.
- W1833042232 hasAuthorship W1833042232A5073853530 @default.
- W1833042232 hasBestOaLocation W18330422321 @default.
- W1833042232 hasConcept C104317684 @default.
- W1833042232 hasConcept C185592680 @default.
- W1833042232 hasConcept C2775905019 @default.
- W1833042232 hasConcept C2777431362 @default.
- W1833042232 hasConcept C2778278337 @default.
- W1833042232 hasConcept C2779138802 @default.
- W1833042232 hasConcept C2779281246 @default.
- W1833042232 hasConcept C515207424 @default.
- W1833042232 hasConcept C55493867 @default.
- W1833042232 hasConcept C71240020 @default.
- W1833042232 hasConceptScore W1833042232C104317684 @default.
- W1833042232 hasConceptScore W1833042232C185592680 @default.
- W1833042232 hasConceptScore W1833042232C2775905019 @default.
- W1833042232 hasConceptScore W1833042232C2777431362 @default.
- W1833042232 hasConceptScore W1833042232C2778278337 @default.
- W1833042232 hasConceptScore W1833042232C2779138802 @default.
- W1833042232 hasConceptScore W1833042232C2779281246 @default.
- W1833042232 hasConceptScore W1833042232C515207424 @default.
- W1833042232 hasConceptScore W1833042232C55493867 @default.
- W1833042232 hasConceptScore W1833042232C71240020 @default.