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- W1833524038 abstract "Surface-active choline esters were prepared by balancing the highly polar quaternary ammonium group in carbamylcholine with non-polar groups at the carbamyl end of the molecule. The new compounds, e.g., di-n-butyl-carbamylcholine chloride, have an atropine-like action on the ocular muscles rather than the muscatine- and nicotine-like effects characterizing previously known choline esters. Di-n-butyl-carbamylcholine has short action and a proportionately greater effect on accommodation than on the pupil while atropine has more prolonged action and a greater effect on the pupil. The new drugs and atropine act synergistically on the iris sphincter." @default.
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- W1833524038 date "1944-03-01" @default.
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- W1833524038 title "CHOLINE ESTERS WITH ATROPINE-LIKE ACTION" @default.
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