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• W1834869689 abstract "When poly(3-hydroxybutyrate) (PHB) scaffold was surface PEGylated with poly(ethylene glycol) methacrylate-block-polystyrene (PS-b-PEGMA), human MG63 osteoblast and HT1080 fibroblast unattached to the PEGylated PHB fibers, but diffusely infiltrated into the hydrated microfibrous scaffold matrix. These cells could grow at reduced cytoskeleton and proliferate within the spatially microenvironment, in which early buildup of neo-tissue construct was stimulated. Biofouling of PEGylated PHB scaffold was controlled, with a remarkably reduction of 90–98% in protein and biological cells adhesions. Besides retaining the original good cytocompatibility, this circumstance was able to activate osteoblast aggregates in the scaffold to up-regulate expression of osteogenesis-related genes, boosting osteogenic differentiation." @default.
• W1834869689 created "2016-06-24" @default.
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• W1834869689 date "2015-06-02" @default.
• W1834869689 modified "2023-09-26" @default.
• W1834869689 title "PEGylated Poly(3-hydroxybutyrate) Scaffold for Hydration-Driven Cell Infiltration, Neo-Tissue Ingrowth, and Osteogenic Potential" @default.
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• W1834869689 doi "https://doi.org/10.1080/00914037.2015.1030657" @default.
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