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• W1835742491 startingPage "568" @default.
• W1835742491 abstract "Genomic footprinting is the method of choice to study (1) the biological relevance of protein–DNA interactions previously established in vitro, (2) the binding sites of factors to identify potential sites for functional analysis, (3) the accessibility of target sites in chromatin, (4) the mechanisms of action of DNA-binding proteins, (5) the action of factors that are unstable during purification, and (6) the occurrence of CpG methylation at specific sites. Besides the agent used to footprint a protein in vivo, the success of the experiment will be largely determined by the occupancy of a given site. Thus, it is of great importance that the cell population to be analyzed be homogeneous with respect to the protein interaction. To establish the significance of a specific effect, it is helpful to use control cells that are treated in parallel with the ones under study." @default.
• W1835742491 created "2016-06-24" @default.
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• W1835742491 date "1993-01-01" @default.
• W1835742491 modified "2023-09-27" @default.
• W1835742491 title "[40] Footprinting of DNA-binding proteins in intact cells" @default.
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• W1835742491 doi "https://doi.org/10.1016/0076-6879(93)18042-b" @default.
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