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- W1837015385 abstract "High performance liquid chromatography (HPLC) has become one of the most powerful tools in contemporary organic analysis as the separation technique that can separate very complex mixtures of compounds and provide qualitative and quantitative information on the sample useful for the identification and determination of sample components. Like gas chromatography (GC), HPLC employs a chromatographic column for the separation. Various modes of HPLC can be applied to the analysis of a large variety of sample types containing non-polar, moderately or strongly polar and ionic compounds, either simple species or high-molecular mass synthetic polymers or biopolymers. These features of HPLC are especially useful in pharmaceutical and clinical analysis. Any chromatographic process requires two phases, the stationary phase and the mobile phase. In HPLC, the stationary phase is formed by a bed of fine solid particles with narrow size distribution, densely packed in a metal, glass or plastic tube—a chromatographic column. The stationary phase may be either the bulk column packing, or only a part of it deposited on or, more frequently, chemically bonded to a more or less inert support material." @default.
- W1837015385 created "2016-06-24" @default.
- W1837015385 creator A5057253656 @default.
- W1837015385 date "2000-01-01" @default.
- W1837015385 modified "2023-10-15" @default.
- W1837015385 title "Chapter 1 Comparison of various modes and phase systems for analytical HPLC" @default.
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- W1837015385 doi "https://doi.org/10.1016/s1567-7192(00)80004-2" @default.
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