FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1837228217> ?p ?o ?g. }

• W1837228217 endingPage "561" @default.
• W1837228217 startingPage "547" @default.
• W1837228217 abstract "We investigated the effects of treatment with tempol (an antioxidant) on vascular and metabolic dysfunction induced by a high-fat high-sucrose (HFHS) diet. Rats were randomized to receive an HFHS or chow diet with or without tempol treatment (1.5 mmol·(kg body mass) −1 ·day −1 ) for 4 weeks. Blood pressure, heart rate, and blood flow were measured in the rats by using intravascular catheters and Doppler flow probes. Insulin sensitivity and vascular responses to insulin were assessed during a euglycemic–hyperinsulinemic clamp. In-vitro studies were performed to evaluate vascular reactivity and endothelial and inducible nitric oxide synthase (eNOS; iNOS) expression in vascular and muscle tissues. Endothelin, nitrotyrosine, and NAD(P)H oxidase expressions were determined in vascular tissues, and glucose transport activity and glucose transporter 4 (GLUT4) expression were examined in muscles. Tempol treatment was found to prevent alterations in insulin sensitivity, glucose transport activity, GLUT4 expression, and vascular reactivity, and to prevent increases in plasma insulin, blood pressure, and heart rate noted in the untreated HFHS-fed rats. These were associated with increased levels of eNOS expression in vascular and muscle tissues, but reductions in nitrotyrosine, endothelin, NAD(P)H oxidase, and iNOS expressions. Therefore, oxidative stress induced by a relatively short-term HFHS diet could contribute to the early development of vascular and metabolic abnormalities in rats." @default.
• W1837228217 created "2016-06-24" @default.
• W1837228217 creator A5026061585 @default.
• W1837228217 creator A5033927550 @default.
• W1837228217 creator A5038466466 @default.
• W1837228217 creator A5064221970 @default.
• W1837228217 creator A5064944124 @default.
• W1837228217 creator A5088974169 @default.
• W1837228217 date "2013-07-01" @default.
• W1837228217 modified "2023-10-17" @default.
• W1837228217 title "Effects of tempol on endothelial and vascular dysfunctions and insulin resistance induced by a high-fat high-sucrose diet in the rat" @default.
• W1837228217 cites W1494780959 @default.
• W1837228217 cites W1724715585 @default.
• W1837228217 cites W1782753704 @default.
• W1837228217 cites W1830229895 @default.
• W1837228217 cites W1910361842 @default.
• W1837228217 cites W1928175618 @default.
• W1837228217 cites W1966584673 @default.
• W1837228217 cites W1972467026 @default.
• W1837228217 cites W1973071643 @default.
• W1837228217 cites W1984483762 @default.
• W1837228217 cites W1985882893 @default.
• W1837228217 cites W2003804374 @default.
• W1837228217 cites W2006567910 @default.
• W1837228217 cites W2008684260 @default.
• W1837228217 cites W2010102296 @default.
• W1837228217 cites W2019814232 @default.
• W1837228217 cites W2020532593 @default.
• W1837228217 cites W2023323317 @default.
• W1837228217 cites W2023632053 @default.
• W1837228217 cites W2030277350 @default.
• W1837228217 cites W2033696113 @default.
• W1837228217 cites W2037605231 @default.
• W1837228217 cites W2037841947 @default.
• W1837228217 cites W2039579026 @default.
• W1837228217 cites W2042111590 @default.
• W1837228217 cites W2052083279 @default.
• W1837228217 cites W2055046559 @default.
• W1837228217 cites W2065501573 @default.
• W1837228217 cites W2066800430 @default.
• W1837228217 cites W2068801993 @default.
• W1837228217 cites W2071548752 @default.
• W1837228217 cites W2072345056 @default.
• W1837228217 cites W2082916190 @default.
• W1837228217 cites W2087434254 @default.
• W1837228217 cites W2087862991 @default.
• W1837228217 cites W2087882379 @default.
• W1837228217 cites W2094974599 @default.
• W1837228217 cites W2101537600 @default.
• W1837228217 cites W2103300387 @default.
• W1837228217 cites W2110827050 @default.
• W1837228217 cites W2111154780 @default.
• W1837228217 cites W2114289687 @default.
• W1837228217 cites W2116611155 @default.
• W1837228217 cites W2117899424 @default.
• W1837228217 cites W2119226138 @default.
• W1837228217 cites W2121498680 @default.
• W1837228217 cites W2122593933 @default.
• W1837228217 cites W2123799914 @default.
• W1837228217 cites W2125060032 @default.
• W1837228217 cites W2126412451 @default.
• W1837228217 cites W2128022125 @default.
• W1837228217 cites W2132666492 @default.
• W1837228217 cites W2133416187 @default.
• W1837228217 cites W2133613922 @default.
• W1837228217 cites W2134945522 @default.
• W1837228217 cites W2138934442 @default.
• W1837228217 cites W2141998216 @default.
• W1837228217 cites W2144153442 @default.
• W1837228217 cites W2147361723 @default.
• W1837228217 cites W2148227152 @default.
• W1837228217 cites W2148637873 @default.
• W1837228217 cites W2151701113 @default.
• W1837228217 cites W2151763612 @default.
• W1837228217 cites W2152746956 @default.
• W1837228217 cites W2153023855 @default.
• W1837228217 cites W2164471793 @default.
• W1837228217 cites W2164884154 @default.
• W1837228217 cites W2165269259 @default.
• W1837228217 cites W2169466315 @default.
• W1837228217 cites W2169553096 @default.
• W1837228217 cites W2184472754 @default.
• W1837228217 cites W2269425308 @default.
• W1837228217 cites W4231154278 @default.
• W1837228217 cites W4250802018 @default.
• W1837228217 cites W4256360470 @default.
• W1837228217 doi "https://doi.org/10.1139/cjpp-2012-0273" @default.
• W1837228217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23826653" @default.
• W1837228217 hasPublicationYear "2013" @default.
• W1837228217 type Work @default.
• W1837228217 sameAs 1837228217 @default.
• W1837228217 citedByCount "13" @default.
• W1837228217 countsByYear W18372282172014 @default.
• W1837228217 countsByYear W18372282172016 @default.
• W1837228217 countsByYear W18372282172017 @default.
• W1837228217 countsByYear W18372282172018 @default.
• W1837228217 countsByYear W18372282172021 @default.
• W1837228217 countsByYear W18372282172022 @default.

• next