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- W1837235904 abstract "Diabetes can be usefully studied at an experimental level by methods that make use of either surgical techniques or chemical agents. Many of the acute metabolic derangements of severe human insulinopenic diabetes can be reproduced by the removal of insulin-producing pancreatic B-cells of the islets of Langerhans. This artificial form of diabetes was first produced by von Mering & Minkowski (1890) when they removed the pancreases of dogs. The same model of diabetes was adopted by Banting & Best (1922) for their historic observations on the hypoglycemic properties of a crude pancreatic extract of insulin." @default.
- W1837235904 created "2016-06-24" @default.
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- W1837235904 date "1990-02-22" @default.
- W1837235904 modified "2023-09-26" @default.
- W1837235904 title "The molecular basis of experimental diabetes" @default.
- W1837235904 doi "https://doi.org/10.1017/cbo9780511600340.012" @default.
- W1837235904 hasPublicationYear "1990" @default.
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