Matches in SemOpenAlex for { <https://semopenalex.org/work/W183728632> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W183728632 endingPage "40" @default.
- W183728632 startingPage "30" @default.
- W183728632 abstract "The assessment of prognosis is a major step in the management of primary cutaneous lymphomas, as it allows to give patients an accurate information and it directs the treatment choice.We performed a literature review of global prognosis and prognostic factors in primary cutaneous lymphomas. We used survival as the main endpoint, in particular specific survival and relative survival which provide accurate estimates of lymphoma-related deaths. Independent prognostic factors identified by multivariate survival analyses were emphasized.Overall prognosis of mycosis fungoides has improved during the past decades, possibly because of an increased proportion of cases diagnosed at early stages. Five-year disease-specific or relative survival rates of patients with T1 stage (patch/plaque disease<10 p. 100 of total skin surface), T2 (> 10 p. 100), T3 (tumor stage) and T4 (generalized erythroderma) are 100 p. 100, 67 to 96 p. 100, 51 to 80 p. 100 and 41 p. 100 respectively. Lymphomatoid papulosis and CD30+ primary cutaneous large T-cell lymphomas have an excellent prognosis, with 5-year survival rates of 100 p. 100 and 96 p. 100 respectively. CD30-negative primary cutaneous large T-cell lymphomas have an aggressive clinical behavior (5-year disease-specific or relative survival: 15 to 21 p. 100). Among primary cutaneous B-cell lymphomas, immunocytomas and marginal-zone B-cell lymphomas are not life-threatening. Follicle center-cell lymphomas that arise on the head and trunk have also an indolent clinical course (5-year specific survival rates: 94 to 97 p. 100). However, few of these lymphomas are composed of more than 50 p. 100 of large cells with round nuclei (centroblasts and/or immunoblasts) and may have a more aggressive clinical course (5-year specific survival: 72 p. 100). Large B-cell lymphomas of the leg often occur in older patients and have a poorer prognosis (5-year specific survival rate: 52 p. 100). Cases with a single lesion and those with a predominance of large cleaved cells (large centrocytes) have a more favorable clinical course than those with multiple tumors or a round cell morphology.Clinical, histological and immunophenotypical prognostic factors which have been identified so far may reliably predict the survival outcome in primary cutaneous lymphomas. On this basis, therapeutic guidelines have been proposed. These prognostic data will have to be taken into account when evaluating new potential prognostic factors (e.g. immunophenotypic or molecular) and performing prospective clinical trials." @default.
- W183728632 created "2016-06-24" @default.
- W183728632 creator A5059800915 @default.
- W183728632 creator A5068469347 @default.
- W183728632 date "2002-01-01" @default.
- W183728632 modified "2023-09-23" @default.
- W183728632 title "[Prognosis of primary cutaneous lymphomas]." @default.
- W183728632 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11937927" @default.
- W183728632 hasPublicationYear "2002" @default.
- W183728632 type Work @default.
- W183728632 sameAs 183728632 @default.
- W183728632 citedByCount "11" @default.
- W183728632 countsByYear W1837286322013 @default.
- W183728632 countsByYear W1837286322017 @default.
- W183728632 crossrefType "journal-article" @default.
- W183728632 hasAuthorship W183728632A5059800915 @default.
- W183728632 hasAuthorship W183728632A5068469347 @default.
- W183728632 hasConcept C121608353 @default.
- W183728632 hasConcept C126322002 @default.
- W183728632 hasConcept C142724271 @default.
- W183728632 hasConcept C143998085 @default.
- W183728632 hasConcept C146357865 @default.
- W183728632 hasConcept C151730666 @default.
- W183728632 hasConcept C16005928 @default.
- W183728632 hasConcept C2776283816 @default.
- W183728632 hasConcept C2777182591 @default.
- W183728632 hasConcept C2777756187 @default.
- W183728632 hasConcept C2778527826 @default.
- W183728632 hasConcept C2778784858 @default.
- W183728632 hasConcept C2779134260 @default.
- W183728632 hasConcept C2779338263 @default.
- W183728632 hasConcept C2779916150 @default.
- W183728632 hasConcept C2780558122 @default.
- W183728632 hasConcept C2780954659 @default.
- W183728632 hasConcept C70905583 @default.
- W183728632 hasConcept C71924100 @default.
- W183728632 hasConcept C86803240 @default.
- W183728632 hasConceptScore W183728632C121608353 @default.
- W183728632 hasConceptScore W183728632C126322002 @default.
- W183728632 hasConceptScore W183728632C142724271 @default.
- W183728632 hasConceptScore W183728632C143998085 @default.
- W183728632 hasConceptScore W183728632C146357865 @default.
- W183728632 hasConceptScore W183728632C151730666 @default.
- W183728632 hasConceptScore W183728632C16005928 @default.
- W183728632 hasConceptScore W183728632C2776283816 @default.
- W183728632 hasConceptScore W183728632C2777182591 @default.
- W183728632 hasConceptScore W183728632C2777756187 @default.
- W183728632 hasConceptScore W183728632C2778527826 @default.
- W183728632 hasConceptScore W183728632C2778784858 @default.
- W183728632 hasConceptScore W183728632C2779134260 @default.
- W183728632 hasConceptScore W183728632C2779338263 @default.
- W183728632 hasConceptScore W183728632C2779916150 @default.
- W183728632 hasConceptScore W183728632C2780558122 @default.
- W183728632 hasConceptScore W183728632C2780954659 @default.
- W183728632 hasConceptScore W183728632C70905583 @default.
- W183728632 hasConceptScore W183728632C71924100 @default.
- W183728632 hasConceptScore W183728632C86803240 @default.
- W183728632 hasIssue "1 Pt 1" @default.
- W183728632 hasLocation W1837286321 @default.
- W183728632 hasOpenAccess W183728632 @default.
- W183728632 hasPrimaryLocation W1837286321 @default.
- W183728632 hasRelatedWork W1584184616 @default.
- W183728632 hasRelatedWork W183728632 @default.
- W183728632 hasRelatedWork W1911378794 @default.
- W183728632 hasRelatedWork W1932831713 @default.
- W183728632 hasRelatedWork W1965205258 @default.
- W183728632 hasRelatedWork W2033692034 @default.
- W183728632 hasRelatedWork W2161989121 @default.
- W183728632 hasRelatedWork W2287829209 @default.
- W183728632 hasRelatedWork W2325111136 @default.
- W183728632 hasRelatedWork W2589757377 @default.
- W183728632 hasVolume "129" @default.
- W183728632 isParatext "false" @default.
- W183728632 isRetracted "false" @default.
- W183728632 magId "183728632" @default.
- W183728632 workType "article" @default.