FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1837297419> ?p ?o ?g. }

• W1837297419 endingPage "35" @default.
• W1837297419 startingPage "35" @default.
• W1837297419 abstract "<p>T cell activation involves positive cellular signals that promote effector functions and negative signals that contribute to the regulation of these responses. These regulatory signals are generated upon activation of receptors on T cells that include CD160, 2B4, Programmed Death-1 and CTLA-4. <strong>Objective</strong>. To evaluate the expression of inhibitory receptors like CD160, 2B4, Programmed Death-1 and CTLA-4 on CD4+ and CD8+ T cells from healthy Colombian donors. <strong>Materials and methods</strong>. Peripheral blood mononuclear cells from 30 healthy donors from Bogotá (Colombia) were obtained via Ficoll-Hypaque density gradient and cells were stained with specific conjugated antibodies previously titrated. <strong>Results</strong>. The CD160, 2B4, and Programmed Death-1 inhibitory markers were detected on CD4+ T cells<br />with expression levels of 0.35%, 1.04%, and 1.35%, respectively. On CD8+ T cells, these markers were expressed at higher levels: 16%, 8.97%, and 4.3%, respectively. In contrast to the other receptors, CTLA-4 frequency of expression showed no significant difference between CD4+ (1.56%) and CD8+ (1.53%) T cells. Frequency of CD160/2B4 and CTLA-4/ Programmed Death-1 coexpression was 0.18% and 0.09% on CD4+ cells, and 4.02% and 0.2% on CD8+ T cells. <strong>Conclusions</strong>. This is the first report showing the frequency of inhibitory receptors such as CD160, 2B4, Programmed Death-1, and CTLA-4 on CD4+ and CD8+ T cells from healthy Colombian donors. Our findings serve as a baseline for the analysis and comparison of these receptors in Colombian populations with different disease conditions.</p><p><br /><strong>Key words</strong>: inhibitory receptors, T cells</p>" @default.
• W1837297419 created "2016-06-24" @default.
• W1837297419 creator A5011339860 @default.
• W1837297419 creator A5055625883 @default.
• W1837297419 creator A5059569658 @default.
• W1837297419 creator A5061953875 @default.
• W1837297419 creator A5063444034 @default.
• W1837297419 creator A5071647777 @default.
• W1837297419 date "2012-01-01" @default.
• W1837297419 modified "2023-09-27" @default.
• W1837297419 title "Expression of inhibitory receptors on CD4+ and CD8+ T cells from healthy Colombian donors" @default.
• W1837297419 cites W1518540044 @default.
• W1837297419 cites W1967758138 @default.
• W1837297419 cites W1975753196 @default.
• W1837297419 cites W1975800926 @default.
• W1837297419 cites W1981431992 @default.
• W1837297419 cites W1990213501 @default.
• W1837297419 cites W2004896918 @default.
• W1837297419 cites W2010671639 @default.
• W1837297419 cites W2016909108 @default.
• W1837297419 cites W2021165507 @default.
• W1837297419 cites W2023858678 @default.
• W1837297419 cites W2041083195 @default.
• W1837297419 cites W2052855154 @default.
• W1837297419 cites W2053677639 @default.
• W1837297419 cites W2076911781 @default.
• W1837297419 cites W2088313410 @default.
• W1837297419 cites W2088541970 @default.
• W1837297419 cites W2090912751 @default.
• W1837297419 cites W2117280652 @default.
• W1837297419 cites W2119896120 @default.
• W1837297419 cites W2123761806 @default.
• W1837297419 cites W2139461240 @default.
• W1837297419 cites W2139496066 @default.
• W1837297419 cites W2152885609 @default.
• W1837297419 cites W2157342679 @default.
• W1837297419 doi "https://doi.org/10.11144/javeriana.sc17-1.eoir" @default.
• W1837297419 hasPublicationYear "2012" @default.
• W1837297419 type Work @default.
• W1837297419 sameAs 1837297419 @default.
• W1837297419 citedByCount "0" @default.
• W1837297419 crossrefType "journal-article" @default.
• W1837297419 hasAuthorship W1837297419A5011339860 @default.
• W1837297419 hasAuthorship W1837297419A5055625883 @default.
• W1837297419 hasAuthorship W1837297419A5059569658 @default.
• W1837297419 hasAuthorship W1837297419A5061953875 @default.
• W1837297419 hasAuthorship W1837297419A5063444034 @default.
• W1837297419 hasAuthorship W1837297419A5071647777 @default.
• W1837297419 hasBestOaLocation W18372974191 @default.
• W1837297419 hasConcept C120642132 @default.
• W1837297419 hasConcept C129374314 @default.
• W1837297419 hasConcept C153911025 @default.
• W1837297419 hasConcept C154317977 @default.
• W1837297419 hasConcept C167672396 @default.
• W1837297419 hasConcept C170493617 @default.
• W1837297419 hasConcept C190283241 @default.
• W1837297419 hasConcept C202751555 @default.
• W1837297419 hasConcept C203014093 @default.
• W1837297419 hasConcept C2776090121 @default.
• W1837297419 hasConcept C31573885 @default.
• W1837297419 hasConcept C55493867 @default.
• W1837297419 hasConcept C86803240 @default.
• W1837297419 hasConcept C8891405 @default.
• W1837297419 hasConcept C95444343 @default.
• W1837297419 hasConceptScore W1837297419C120642132 @default.
• W1837297419 hasConceptScore W1837297419C129374314 @default.
• W1837297419 hasConceptScore W1837297419C153911025 @default.
• W1837297419 hasConceptScore W1837297419C154317977 @default.
• W1837297419 hasConceptScore W1837297419C167672396 @default.
• W1837297419 hasConceptScore W1837297419C170493617 @default.
• W1837297419 hasConceptScore W1837297419C190283241 @default.
• W1837297419 hasConceptScore W1837297419C202751555 @default.
• W1837297419 hasConceptScore W1837297419C203014093 @default.
• W1837297419 hasConceptScore W1837297419C2776090121 @default.
• W1837297419 hasConceptScore W1837297419C31573885 @default.
• W1837297419 hasConceptScore W1837297419C55493867 @default.
• W1837297419 hasConceptScore W1837297419C86803240 @default.
• W1837297419 hasConceptScore W1837297419C8891405 @default.
• W1837297419 hasConceptScore W1837297419C95444343 @default.
• W1837297419 hasIssue "1" @default.
• W1837297419 hasLocation W18372974191 @default.
• W1837297419 hasLocation W18372974192 @default.
• W1837297419 hasOpenAccess W1837297419 @default.
• W1837297419 hasPrimaryLocation W18372974191 @default.
• W1837297419 hasRelatedWork W1488847325 @default.
• W1837297419 hasRelatedWork W1642471596 @default.
• W1837297419 hasRelatedWork W1991131776 @default.
• W1837297419 hasRelatedWork W1996511424 @default.
• W1837297419 hasRelatedWork W2050378540 @default.
• W1837297419 hasRelatedWork W2079772070 @default.
• W1837297419 hasRelatedWork W2080619320 @default.
• W1837297419 hasRelatedWork W2157183976 @default.
• W1837297419 hasRelatedWork W2352231447 @default.
• W1837297419 hasRelatedWork W2356076720 @default.
• W1837297419 hasRelatedWork W2356653246 @default.
• W1837297419 hasRelatedWork W2378115995 @default.
• W1837297419 hasRelatedWork W2393477958 @default.
• W1837297419 hasRelatedWork W2418711909 @default.

• next