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- W1837334890 abstract "Starvation (24h) increased the maximum activity of carnitine palmitoyltransferase 1 in rat liver and increased the concentration of malonyl-CoA required to cause 50% inhibition of the enzyme (I50). Re-feeding (24h) with a standard cube diet or a high-carbohydrate diet reversed both of these changes, whereas re-feeding with a high-fat diet did not. Administration of cycloheximide (200 micrograms/100 g body wt.) blocked the increases in carnitine palmitoyltransferase 1 activity and I50 on starvation. It is suggested that increase in carnitine palmitoyltransferase 1 activity in starvation may involve synthesis of new enzyme." @default.
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- W1837334890 date "1984-11-15" @default.
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- W1837334890 title "Cycloheximide blocks changes in rat liver carnitine palmitoyltransferase 1 activity in starvation" @default.
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- W1837334890 doi "https://doi.org/10.1042/bj2240201" @default.
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