FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1837356759> ?p ?o ?g. }

• W1837356759 abstract "Mild to moderate traumatic brain injury (TBI) is associated with increased risk of Post-Traumatic Stress Disorder (PTSD) in returning veterans of the Iraq and Afghanistan wars. Evidence from neuroimaging and neuropsychological studies suggests that PTSD and TBI may share a common neural network, and that disruption of this network may increase the risk of developing PTSD symptoms. The purpose of this study was to investigate the overlapping neuropsychological and neuroanatomical substrates of PTSD and TBI within a sample of veterans. We predicted that both TBI and increasing PTSD symptom severity would be associated with poorer neuropsychological performance, lower integrity of white matter fiber bundles, and thinning of the frontal and temporal cortical regions. A final sample of 38 veterans [ages 21-50; mild: n=33; moderate: n=5)] approximately four years removed from their TBI event(s) were compared to 17 veterans without a history of TBI. Assessments included neuroimaging, cognitive testing, a detailed TBI interview, and the Post-traumatic Stress Disorder Check List-Military Version (PCL-M). Cortical thickness measures were derived from structural MR imaging, and measures of white matter integrity were derived from diffusion tensor imaging. Compared to control participants the TBI group had higher PCL-M scores (p<.01), lower white matter integrity in the cingulum bundle (p<.01) and the genu (p< .05), poorer memory performance and slower processing speed (p's<.05). Slower processing speed was associated with lower white matter integrity across many white matter pathways (p-values ranged from <.001-.05). Higher PCL-M scores were associated with cortical thinning of the left orbitofrontal cortex (p<.05) and unexpectedly with lower diffusion in the fornix (p<.05). The results found little evidence for a disrupted common network between TBI and PTSD. Instead, they support unique and non-overlapping effects of TBI and PTSD symptom severity such that TBI is associated with deficits in memory and processing speed, and disrupted frontal white matter myelin integrity, whereas PTSD was associated with thinning of a cortical region associated with emotional regulation. Results suggest that persisting neurocognitive deficits may be associated with TBI-related disrupted myelin integrity to a greater degree than comorbid psychiatric illness" @default.
• W1837356759 created "2016-06-24" @default.
• W1837356759 creator A5068832079 @default.
• W1837356759 date "2013-01-01" @default.
• W1837356759 modified "2023-09-28" @default.
• W1837356759 title "Traumatic Brain Injury and Post-Traumatic Stress Disorder Symptoms in OEF/OIF Veterans : : A Combined Diffusion Tensor Imaging and Cortical Thickness Study" @default.
• W1837356759 cites W1237789907 @default.
• W1837356759 cites W1483687681 @default.
• W1837356759 cites W1498057507 @default.
• W1837356759 cites W1563000606 @default.
• W1837356759 cites W1564331199 @default.
• W1837356759 cites W1568390176 @default.
• W1837356759 cites W1592331102 @default.
• W1837356759 cites W1603121691 @default.
• W1837356759 cites W1741090988 @default.
• W1837356759 cites W1793501383 @default.
• W1837356759 cites W1799774687 @default.
• W1837356759 cites W1835825865 @default.
• W1837356759 cites W1923946347 @default.
• W1837356759 cites W1964851255 @default.
• W1837356759 cites W1967313717 @default.
• W1837356759 cites W1969426010 @default.
• W1837356759 cites W1970107990 @default.
• W1837356759 cites W1971459427 @default.
• W1837356759 cites W1971896998 @default.
• W1837356759 cites W1973367937 @default.
• W1837356759 cites W1973893263 @default.
• W1837356759 cites W1976927833 @default.
• W1837356759 cites W1977045648 @default.
• W1837356759 cites W1977997484 @default.
• W1837356759 cites W1981630211 @default.
• W1837356759 cites W1982055979 @default.
• W1837356759 cites W1983355263 @default.
• W1837356759 cites W1984800913 @default.
• W1837356759 cites W1986008527 @default.
• W1837356759 cites W1989058637 @default.
• W1837356759 cites W1990525339 @default.
• W1837356759 cites W1992436988 @default.
• W1837356759 cites W1993327231 @default.
• W1837356759 cites W1994026785 @default.
• W1837356759 cites W1994972002 @default.
• W1837356759 cites W1998817411 @default.
• W1837356759 cites W1999827600 @default.
• W1837356759 cites W2004156913 @default.
• W1837356759 cites W2005209923 @default.
• W1837356759 cites W2005394755 @default.
• W1837356759 cites W2006096283 @default.
• W1837356759 cites W2008552409 @default.
• W1837356759 cites W2008655880 @default.
• W1837356759 cites W2009211323 @default.
• W1837356759 cites W2010246361 @default.
• W1837356759 cites W2011027589 @default.
• W1837356759 cites W2011383306 @default.
• W1837356759 cites W2012272606 @default.
• W1837356759 cites W2012594924 @default.
• W1837356759 cites W2016108891 @default.
• W1837356759 cites W2021865008 @default.
• W1837356759 cites W2023349410 @default.
• W1837356759 cites W2023819682 @default.
• W1837356759 cites W2025639109 @default.
• W1837356759 cites W2025911957 @default.
• W1837356759 cites W2026812901 @default.
• W1837356759 cites W2027453180 @default.
• W1837356759 cites W2029086834 @default.
• W1837356759 cites W2031504469 @default.
• W1837356759 cites W2035079822 @default.
• W1837356759 cites W2036785860 @default.
• W1837356759 cites W2037282107 @default.
• W1837356759 cites W2038862135 @default.
• W1837356759 cites W2049689895 @default.
• W1837356759 cites W2052019737 @default.
• W1837356759 cites W2054642828 @default.
• W1837356759 cites W2055500414 @default.
• W1837356759 cites W2055504658 @default.
• W1837356759 cites W2057303012 @default.
• W1837356759 cites W2058668959 @default.
• W1837356759 cites W2062419087 @default.
• W1837356759 cites W2063973660 @default.
• W1837356759 cites W2065205627 @default.
• W1837356759 cites W2067658969 @default.
• W1837356759 cites W2068710494 @default.
• W1837356759 cites W2069058065 @default.
• W1837356759 cites W2070594067 @default.
• W1837356759 cites W2071138914 @default.
• W1837356759 cites W2072058015 @default.
• W1837356759 cites W2074678189 @default.
• W1837356759 cites W2076737486 @default.
• W1837356759 cites W2078347439 @default.
• W1837356759 cites W2078597721 @default.
• W1837356759 cites W2081237186 @default.
• W1837356759 cites W2086858670 @default.
• W1837356759 cites W2087170847 @default.
• W1837356759 cites W2087393332 @default.
• W1837356759 cites W2088858548 @default.
• W1837356759 cites W2095792933 @default.
• W1837356759 cites W2096485330 @default.
• W1837356759 cites W2096859537 @default.
• W1837356759 cites W2097713446 @default.
• W1837356759 cites W2099086958 @default.
• W1837356759 cites W2100549080 @default.

• next