Matches in SemOpenAlex for { <https://semopenalex.org/work/W1837364944> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1837364944 endingPage "8" @default.
- W1837364944 startingPage "1" @default.
- W1837364944 abstract "Tetanus is a disease that occurs in humans and various animal species worldwide. Tetanus toxin, after binding itself to nerve structures in the spinal cord, blocking the release of inhibitory transmitors which results in predominance of excitatory transmitors, and this manifestes itself in skeletal muscle spasm. In theory, inhibition of excitatory transmission can try to antagonize a number of ways: by stimulating inhibitory transmission with application inhibitory transmitors, inhibition of excitatory transmission by application of antagonists of excitatory transmitors and combination of antagonists of excitatory transmitors. Bearing this in mind, we attempted to normalize the disorders by tetanus toxin with the use of caroverine, an antagonist of excitatory transmitors, alone and in combination with aminooxyacetic acid (substance that increases the level of GABA). Experiments were conducted on albino mice of both sexes, weight 20-25 g. The experimental tetanus was induced by application of tetanus toxin. The application of caroverine and combination with aminooxyacetic acid was carried out 24 hours after application of tetanus toxin, once per day, until the death. Caroverine, given alone in a dose of 1,2 mg/kg significantly prolonged the LD50 period of mice with experimental tetanus, so the obtained results can be said that its application only at this dose proved to be effective. The combination with aminooxyacetic acid was gave an insignificant extension of mice’s dying time with experimental tetanus in the trial, compared to the control group. Key words: tetanus, tetanus toxin, transmitors, caroverine, aminooxyacetic acid" @default.
- W1837364944 created "2016-06-24" @default.
- W1837364944 creator A5003098712 @default.
- W1837364944 creator A5034225776 @default.
- W1837364944 creator A5043164846 @default.
- W1837364944 date "2011-01-01" @default.
- W1837364944 modified "2023-09-26" @default.
- W1837364944 title "THE EFFECT OF CAROVERINE AND ITS COMBINATION WITH AMINOOXYACETIC ACID ON SURVIVAL TIME OF MICE WITH EXPERIMENTAL TETANUS" @default.
- W1837364944 hasPublicationYear "2011" @default.
- W1837364944 type Work @default.
- W1837364944 sameAs 1837364944 @default.
- W1837364944 citedByCount "1" @default.
- W1837364944 countsByYear W18373649442018 @default.
- W1837364944 crossrefType "journal-article" @default.
- W1837364944 hasAuthorship W1837364944A5003098712 @default.
- W1837364944 hasAuthorship W1837364944A5034225776 @default.
- W1837364944 hasAuthorship W1837364944A5043164846 @default.
- W1837364944 hasConcept C112592302 @default.
- W1837364944 hasConcept C126322002 @default.
- W1837364944 hasConcept C170493617 @default.
- W1837364944 hasConcept C17077164 @default.
- W1837364944 hasConcept C181199279 @default.
- W1837364944 hasConcept C185592680 @default.
- W1837364944 hasConcept C203014093 @default.
- W1837364944 hasConcept C22070199 @default.
- W1837364944 hasConcept C2776627618 @default.
- W1837364944 hasConcept C2776885963 @default.
- W1837364944 hasConcept C2777367657 @default.
- W1837364944 hasConcept C2779841045 @default.
- W1837364944 hasConcept C42219234 @default.
- W1837364944 hasConcept C55493867 @default.
- W1837364944 hasConcept C71924100 @default.
- W1837364944 hasConcept C98274493 @default.
- W1837364944 hasConceptScore W1837364944C112592302 @default.
- W1837364944 hasConceptScore W1837364944C126322002 @default.
- W1837364944 hasConceptScore W1837364944C170493617 @default.
- W1837364944 hasConceptScore W1837364944C17077164 @default.
- W1837364944 hasConceptScore W1837364944C181199279 @default.
- W1837364944 hasConceptScore W1837364944C185592680 @default.
- W1837364944 hasConceptScore W1837364944C203014093 @default.
- W1837364944 hasConceptScore W1837364944C22070199 @default.
- W1837364944 hasConceptScore W1837364944C2776627618 @default.
- W1837364944 hasConceptScore W1837364944C2776885963 @default.
- W1837364944 hasConceptScore W1837364944C2777367657 @default.
- W1837364944 hasConceptScore W1837364944C2779841045 @default.
- W1837364944 hasConceptScore W1837364944C42219234 @default.
- W1837364944 hasConceptScore W1837364944C55493867 @default.
- W1837364944 hasConceptScore W1837364944C71924100 @default.
- W1837364944 hasConceptScore W1837364944C98274493 @default.
- W1837364944 hasLocation W18373649441 @default.
- W1837364944 hasOpenAccess W1837364944 @default.
- W1837364944 hasPrimaryLocation W18373649441 @default.
- W1837364944 hasRelatedWork W1868741604 @default.
- W1837364944 hasRelatedWork W1967250928 @default.
- W1837364944 hasRelatedWork W1972940484 @default.
- W1837364944 hasRelatedWork W1973769313 @default.
- W1837364944 hasRelatedWork W1986679543 @default.
- W1837364944 hasRelatedWork W1990296246 @default.
- W1837364944 hasRelatedWork W1993455555 @default.
- W1837364944 hasRelatedWork W1993882683 @default.
- W1837364944 hasRelatedWork W1998431479 @default.
- W1837364944 hasRelatedWork W2018826895 @default.
- W1837364944 hasRelatedWork W2038029107 @default.
- W1837364944 hasRelatedWork W2090746372 @default.
- W1837364944 hasRelatedWork W2143133343 @default.
- W1837364944 hasRelatedWork W2155148894 @default.
- W1837364944 hasRelatedWork W2412783395 @default.
- W1837364944 hasRelatedWork W2414414343 @default.
- W1837364944 hasRelatedWork W2415307598 @default.
- W1837364944 hasRelatedWork W2416560933 @default.
- W1837364944 hasRelatedWork W2503743476 @default.
- W1837364944 hasRelatedWork W2240510721 @default.
- W1837364944 hasVolume "60" @default.
- W1837364944 isParatext "false" @default.
- W1837364944 isRetracted "false" @default.
- W1837364944 magId "1837364944" @default.
- W1837364944 workType "article" @default.