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- W1837403142 abstract "Aim: Several factors including genetic factors nutrition and environment play a critical role in the growth of children Adenotonsillar hypertrophy ATH can cause growth retardation by obstructing the upper airway Surgical treatment of ATH has been considered to have a positive effect on growth The aim of this study was to evaluate the role of chronic ATH on growth by measuring weight height body mass index BMI bone age serum insulin like growth factor 1 IGF 1 and insulin like growth factor binding protein 3 IGFBP 3 values before and after adenotonsillectomy Material and Method: The study was approved by the Ethics Committee 4 5 2004; 04 170 and written informed consents were obtained from parents of the participants A total of 40 prepubertal children who were diagnosed as chronic ATH were enrolled Obstructive symptoms were questioned in the medical history before surgery Weight height BMI and bone age values were measured and compared with reference values Preoperative serum IGF 1 and IGFBP 3 values were compared with the control group which consisted of healthy children Rates of obstructive symptoms weight height BMI bone age serum IGF 1 and IGFBP 3 values of the patients were determined seven months after adenotonsillectomy and were compared with preoperative values Results: Obstructive symptoms in children with ATH decreased remarkably after surgery Preoperative mean value of bone age of the patients was statistically lower than reference values p lt;0 05 and mean value of serum IGF 1 was lower than than the control group p lt;0 05 IGF 1 and IGFBP 3 values did not increase significantly after surgery p gt;0 05 However growth retardation was detected in three out of 40 patients based on the anthropometric measurements Conclusions: In this study antropometric findings showed that chronic ATH did not cause significant growth retardation in prepubertal children In addition we could not prove that surgical treatment of ATH improved the growth in the postoperative follow up period of seven months This result may be related with our study population with a limited number of patients who had baseline growth retardation and short postoperative follow up period Further studies with large number of patients and longer postoperative follow up periods are required to determine the exact role of chronic ATH in growth retardation Turk Arch Ped 2012; 47: 260 6" @default.
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- W1837403142 date "2012-12-15" @default.
- W1837403142 modified "2023-10-14" @default.
- W1837403142 title "Çocuklarda kronik adenotonsiller hipertrofinin büyüme üzerine etkilerinin adenotonsillektomi öncesi ve sonrası dönemde değerlendirilmesi" @default.
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- W1837403142 doi "https://doi.org/10.4274/tpa.904" @default.
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