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- W1837585811 abstract "To compare the pharmacokinetic differences of chloroquine in normal mice and the mice infected with the N and the RC strains of Plasmodium berghei.The concentrations of chloroquine in the plasma of normal mice and the mice infected with the N or the RC strains of P. berghei were analyzed by reverse-phase HPLC. The pharmacokinetic parameters were measured with software 3P87.The t1/2 beta value was significantly lower in the mice infected with the RC strain than in normal mice and the mice infected with the N strain(P < 0.05), however, there were no significant differences between the mice infected with the N strain and normal mice.Elimination of chloroquine in the mice infected with the RC strain of P. berghei speed up significantly comparing with the mice infected with the N strain." @default.
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- W1837585811 date "2000-01-01" @default.
- W1837585811 modified "2023-09-26" @default.
- W1837585811 title "[Studies on pharmacokinetics of chloroquine in mice infected with chloroquine-resistant strain of Plasmodium berghei]." @default.
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