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• W1837841244 abstract "Blood viscosity and its major determinants (hematocrit, plasma fibrinogen, and plasma viscosity) were measured in 25 men, 25 women who were not using oral contraceptives, and 25 women who had been using oral contraceptives for at least 3 months. Mean blood viscosity and hematocrit were significantly higher in women using oral contraceptives than in women who were not (p < 0.001), and use of oral contraceptives abolished the normal sex difference in blood viscosity and hematocrit. After correction to a standard hematocrit of 45%, blood viscosity was still higher in users or oral contraceptives, as was plasma fibrinogen (p < 0.05). Plasma viscosity was not significantly increased in users of oral contraceptives.25 male and 50 female healthy volunteers were studied cross-sectionally to determine the effects of oral contraceptive (OC) usage on blood viscosity parameters (blood viscosity, hematocrit, fibrinogen, and plasma viscosity). Mean blood viscosity and mean hematocrit were significantly higher in men than in women not using OCs (p .001). In women using OCs (all estrogen-containing), mean blood viscosity and mean hematocrit were significantly higher than in nonusers (p .001) and not significantly different from male values (p .1). Blood viscosity correlated linearly with hematocrit. Mean blood viscosity was significantly higher in women using OCs than in nonusers or men (p .05). Plasma fibrinogen was significantl increased in OC users compared with nonusers (p .05) but not compared with men (p .1). Plasma viscosity was not significantly elevated in users of OCs (p .1). Fibrinogen correlated with corrected blood viscosity and plasma viscosity (r=.38 and r=.55, respectively). No significant differences in blood viscosity or its determinants were found when women who smoked were compared with nonsmokers or when users of OCs containing 30 mcg of estrogen were compared with users of 50 mcg preparations. Further studies are required to determine the role of blood viscosity in the development of circulatory complications of OC use." @default.
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• W1837841244 date "1980-08-01" @default.
• W1837841244 modified "2023-10-06" @default.
• W1837841244 title "Increased blood viscosity in young women using oral contraceptives" @default.
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• W1837841244 doi "https://doi.org/10.1016/0002-9378(80)90896-0" @default.
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