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- W1837910717 abstract "We have investigated the expression of TLR2 and Dectin-1 in retinal microglia and their involvement in Candida albicans phagocytosis using a cytometric approach. The expression of both receptors has been demonstrated in CD11b(+) retinal cells. Phagocytosis of pHrodo-labelled C. albicans yeasts by microglial CD11b(+) cells of C57BL/6 mice was inhibited both by the Dectin-1 antagonist laminarin and anti-Dectin-1 antibodies, whereas phagocytosis of yeasts by retinal microglia of TLR2 KO mice was unaffected. These data indicate that phagocytosis of C. albicans yeasts by retinal microglia is mediated by Dectin-1, whereas TLR2 does not play a significant role in this process." @default.
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- W1837910717 date "2011-10-01" @default.
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- W1837910717 title "Dectin-1 mediates<i>in vitro</i>phagocytosis of<i>Candida albicans</i>yeast cells by retinal microglia: Figure 1" @default.
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- W1837910717 doi "https://doi.org/10.1111/j.1574-695x.2011.00829.x" @default.
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