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- W1838256894 abstract "A series of 5-(piperidinylethyloxy)quinoline 5-HT(1) receptor ligands have been studied by elaboration of the series of dual 5-HT(1)-SSRIs reported previously. These new compounds display a different in vitro pharmacological profile with potent affinity across the 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptors and selectivity against the serotonin transporter. Furthermore, they have improved pharmacokinetic profiles and CNS penetration." @default.
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- W1838256894 date "2009-01-01" @default.
- W1838256894 modified "2023-09-27" @default.
- W1838256894 title "Studies on a series of potent, orally bioavailable, 5-HT1 receptor ligands—Part II" @default.
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- W1838256894 doi "https://doi.org/10.1016/j.bmcl.2008.11.052" @default.
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