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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1838264472> ?p ?o ?g. }

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• W1838264472 abstract "alpha-Sarcin is a cytotoxic protein produced by the mould Aspergillus giganteus. Insertion of alpha-sarcin into asolectin membranes has been demonstrated by protein labelling with photoreactive phospholipids. alpha-Sarcin added externally to tRNA-containing asolectin liposomes degrades the entrapped tRNA. Trypsin-containing asolectin liposomes were also prepared. Encapsulated trypsin degrades alpha-sarcin, even in the presence of a large excess of external hen egg-white trypsin inhibitor to prevent any alpha-sarin degradation outside the vesicles. These processes occur only with acidic phospholipids and were not observed when phosphatidylcholine vesicles were used. These results indicate that alpha-sarcin penetrates the lipid bilayer and becomes exposed to the lumen of negatively charged liposomes." @default.
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• W1838264472 date "1993-10-01" @default.
• W1838264472 modified "2023-10-03" @default.
• W1838264472 title "Translocation of α-sarcin across the lipid bilayer of asolectin vesicles" @default.
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• W1838264472 doi "https://doi.org/10.1042/bj2950221" @default.
• W1838264472 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1134842" @default.
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