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- W1838642084 abstract "Publisher Summary This chapter discusses the synthesis of nucleic acids and proteins in the spiralian embryo. The spiralian egg is unique because of its determinant cleavage— that is, the blastomeres —resulting from the early divisions of the egg are not equal in their ability to differentiate. The relation of nucleic acids and protein syntheses to the phases of embryogenesis is valuable because these syntheses are the results and the operational criteria of gene transcription. A study of the effect of actinomycin D on the synthesis of RNA, DNA, and protein and on the differentiation in the Ilyanassa embryo is described in this chapter. From these results, it is concluded that in this spiralian embryo: (1) cleavage and gastrulation do not require concurrent transcription of the genome, (2) the genome is not completely repressed during early development, (3) transcription of the genome precedes visible morphogenesis, and (4) the messenger RNAs that program the protein synthesis required for differentiation are probably stable. From the relation of the time of treatment with actinomycin D and subsequent differentiation, a tentative schedule of gene transcription is presented for this embryo. Some results on the role of the polar lobe in development and the relation of precocious segregation to the reading of the genome are discussed in this chapter." @default.
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- W1838642084 date "1966-01-01" @default.
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- W1838642084 title "Chapter 2 The Transcription of Genetic Information in the Spiralian Embryo" @default.
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- W1838642084 doi "https://doi.org/10.1016/s0070-2153(08)60008-3" @default.
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