FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1838851706> ?p ?o ?g. }

• W1838851706 endingPage "587" @default.
• W1838851706 startingPage "579" @default.
• W1838851706 abstract "Statins have been shown to possess favourable effects on the cardiovascular system with stabilization of the vulnerable plaque. We sought to assess the effects of early aggressive statin treatment on plaque composition in patients with acute myocardial infarction (AMI), using serial assessment with coronary CT-angiography (CTA).In a prospective randomized blinded endpoint trial patients with AMI were randomized to an intensive lipid lowering treatment receiving statin loading with 80 mg rosuvastatin followed by 40 mg daily or standard statin therapy according to current guidelines. Patients were assessed with CTA at baseline and after 12 months with evaluation of plaque volume and composition.In total, 140 patients with AMI were randomized and plaque composition was assessed in 96 patients. In the intensive care group LDL-level was median 1.3 [0.9; 1.5] mmol/l at 12 months follow-up and 2.0 [1.7; 2.4] mmol/l in the usual care group, p < 0.001. Plaque volume increased over 12 months with 43.5 (±225.8) mm(3) in the intensive care group and 19.1 (±190.2) mm(3) in the usual care group, p = 0.57. Plaque composition changed over 12 months with an increase in total dense calcium volume by 11.1 (±39.6) mm(3), corresponding to a 23% increase, in the intensive care group and a decreased by -0.4 (±26.6) mm(3) in the usual care group, p < 0.001. Necrotic core volume increased 26.8 (±122.1) mm(3) in the intensive care group and 25.2 (±80.1) mm(3) in the usual care group, p = 0.94.Early aggressive lipid lowering therapy significantly increases dense calcium volume in patients with AMI." @default.
• W1838851706 created "2016-06-24" @default.
• W1838851706 creator A5005343373 @default.
• W1838851706 creator A5026014519 @default.
• W1838851706 creator A5033737243 @default.
• W1838851706 creator A5048496472 @default.
• W1838851706 creator A5053535508 @default.
• W1838851706 creator A5058398277 @default.
• W1838851706 creator A5059520666 @default.
• W1838851706 creator A5077774990 @default.
• W1838851706 creator A5081523490 @default.
• W1838851706 creator A5089780642 @default.
• W1838851706 date "2015-08-01" @default.
• W1838851706 modified "2023-10-13" @default.
• W1838851706 title "Effects of intensive lipid-lowering therapy on coronary plaques composition in patients with acute myocardial infarction: Assessment with serial coronary CT angiography" @default.
• W1838851706 cites W113768872 @default.
• W1838851706 cites W16027210 @default.
• W1838851706 cites W193971504 @default.
• W1838851706 cites W1972268271 @default.
• W1838851706 cites W1986631172 @default.
• W1838851706 cites W1990304849 @default.
• W1838851706 cites W1996344483 @default.
• W1838851706 cites W2000073805 @default.
• W1838851706 cites W2007448220 @default.
• W1838851706 cites W2015795623 @default.
• W1838851706 cites W2018637416 @default.
• W1838851706 cites W2020299738 @default.
• W1838851706 cites W2021023597 @default.
• W1838851706 cites W2024105966 @default.
• W1838851706 cites W2033172078 @default.
• W1838851706 cites W2033519163 @default.
• W1838851706 cites W2035499465 @default.
• W1838851706 cites W2055057774 @default.
• W1838851706 cites W2064519207 @default.
• W1838851706 cites W2065023636 @default.
• W1838851706 cites W2067348877 @default.
• W1838851706 cites W2069183328 @default.
• W1838851706 cites W2069557124 @default.
• W1838851706 cites W2079289240 @default.
• W1838851706 cites W2082324316 @default.
• W1838851706 cites W2085319008 @default.
• W1838851706 cites W2087666115 @default.
• W1838851706 cites W2088861718 @default.
• W1838851706 cites W2090214288 @default.
• W1838851706 cites W2105049460 @default.
• W1838851706 cites W2112360098 @default.
• W1838851706 cites W2120439472 @default.
• W1838851706 cites W2121363804 @default.
• W1838851706 cites W2129750583 @default.
• W1838851706 cites W2131370832 @default.
• W1838851706 cites W2134343469 @default.
• W1838851706 cites W2146228563 @default.
• W1838851706 cites W2149378542 @default.
• W1838851706 cites W2159449551 @default.
• W1838851706 cites W2160152341 @default.
• W1838851706 cites W2161351985 @default.
• W1838851706 cites W2272962241 @default.
• W1838851706 cites W2322095705 @default.
• W1838851706 cites W3030817736 @default.
• W1838851706 cites W4240900378 @default.
• W1838851706 cites W424467158 @default.
• W1838851706 doi "https://doi.org/10.1016/j.atherosclerosis.2015.06.007" @default.
• W1838851706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26115069" @default.
• W1838851706 hasPublicationYear "2015" @default.
• W1838851706 type Work @default.
• W1838851706 sameAs 1838851706 @default.
• W1838851706 citedByCount "52" @default.
• W1838851706 countsByYear W18388517062014 @default.
• W1838851706 countsByYear W18388517062015 @default.
• W1838851706 countsByYear W18388517062016 @default.
• W1838851706 countsByYear W18388517062017 @default.
• W1838851706 countsByYear W18388517062018 @default.
• W1838851706 countsByYear W18388517062019 @default.
• W1838851706 countsByYear W18388517062020 @default.
• W1838851706 countsByYear W18388517062021 @default.
• W1838851706 countsByYear W18388517062022 @default.
• W1838851706 countsByYear W18388517062023 @default.
• W1838851706 crossrefType "journal-article" @default.
• W1838851706 hasAuthorship W1838851706A5005343373 @default.
• W1838851706 hasAuthorship W1838851706A5026014519 @default.
• W1838851706 hasAuthorship W1838851706A5033737243 @default.
• W1838851706 hasAuthorship W1838851706A5048496472 @default.
• W1838851706 hasAuthorship W1838851706A5053535508 @default.
• W1838851706 hasAuthorship W1838851706A5058398277 @default.
• W1838851706 hasAuthorship W1838851706A5059520666 @default.
• W1838851706 hasAuthorship W1838851706A5077774990 @default.
• W1838851706 hasAuthorship W1838851706A5081523490 @default.
• W1838851706 hasAuthorship W1838851706A5089780642 @default.
• W1838851706 hasConcept C126322002 @default.
• W1838851706 hasConcept C164705383 @default.
• W1838851706 hasConcept C168563851 @default.
• W1838851706 hasConcept C177713679 @default.
• W1838851706 hasConcept C203092338 @default.
• W1838851706 hasConcept C2776376669 @default.
• W1838851706 hasConcept C2776839432 @default.
• W1838851706 hasConcept C2780499067 @default.
• W1838851706 hasConcept C2987404301 @default.
• W1838851706 hasConcept C500558357 @default.

• next