Matches in SemOpenAlex for { <https://semopenalex.org/work/W1838893374> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1838893374 endingPage "496" @default.
- W1838893374 startingPage "491" @default.
- W1838893374 abstract "Coronary artery disease (CAD) is a multifactorial disease in which genetic and environmental factors play an important role. These factors differ in each population. This study was carried out to determine whether there is an association between insertion/deletion (I/D) polymorphism and CAD in Turkish patients from Ankara. An I/D polymorphism in intron 16 of the gene coding for the angiotensin-converting enzyme (ACE) has been used to study the role of this gene in the aetiology of coronary atherosclerosis and hypertension. As there are no existing data for the Turkish population, we studied the I/D polymorphism of the ACE gene in 218 patients with CAD and 107 controls. Polymerase chain reaction (PCR) was used for genotyping the I and D alleles. The DD polymorphism of the ACE gene was significantly different between CAD subjects (0.733) and controls (0.612) (p=0.002). The observed heterozygosity was 29.3% and 43.9% and D allele frequency was 0.733 and 0.612, respectively. There was a significantly higher D allele (p=0.03) in 111 patients with myocardial infarction (MI) compared with controls. Furthermore, MI localization also gave a significance of p=0.002 for inferior MI but not for anterior MI (p=0.83). Forty-three hypertension patients had a D allele frequency of 0.767 which was significantly different from control (p=0.01). These data provide further evidence for the association of D allele and CAD in a Turkish population." @default.
- W1838893374 created "2016-06-24" @default.
- W1838893374 creator A5011834144 @default.
- W1838893374 creator A5012821547 @default.
- W1838893374 creator A5063458144 @default.
- W1838893374 creator A5082504401 @default.
- W1838893374 date "1998-01-01" @default.
- W1838893374 modified "2023-09-26" @default.
- W1838893374 title "Deletion polymorphism at the angiotensin-converting enzyme gene in Turkish patients with coronary artery disease" @default.
- W1838893374 cites W1987328145 @default.
- W1838893374 cites W1992355300 @default.
- W1838893374 cites W1993252513 @default.
- W1838893374 cites W2013709047 @default.
- W1838893374 cites W2024841768 @default.
- W1838893374 cites W2072262664 @default.
- W1838893374 cites W2080452768 @default.
- W1838893374 cites W2312388685 @default.
- W1838893374 cites W2338539226 @default.
- W1838893374 doi "https://doi.org/10.1080/00365519850186292" @default.
- W1838893374 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9832341" @default.
- W1838893374 hasPublicationYear "1998" @default.
- W1838893374 type Work @default.
- W1838893374 sameAs 1838893374 @default.
- W1838893374 citedByCount "37" @default.
- W1838893374 countsByYear W18388933742013 @default.
- W1838893374 countsByYear W18388933742015 @default.
- W1838893374 countsByYear W18388933742016 @default.
- W1838893374 countsByYear W18388933742019 @default.
- W1838893374 crossrefType "journal-article" @default.
- W1838893374 hasAuthorship W1838893374A5011834144 @default.
- W1838893374 hasAuthorship W1838893374A5012821547 @default.
- W1838893374 hasAuthorship W1838893374A5063458144 @default.
- W1838893374 hasAuthorship W1838893374A5082504401 @default.
- W1838893374 hasConcept C104317684 @default.
- W1838893374 hasConcept C126322002 @default.
- W1838893374 hasConcept C135763542 @default.
- W1838893374 hasConcept C180754005 @default.
- W1838893374 hasConcept C27016395 @default.
- W1838893374 hasConcept C2778213512 @default.
- W1838893374 hasConcept C2778817970 @default.
- W1838893374 hasConcept C2908647359 @default.
- W1838893374 hasConcept C31467283 @default.
- W1838893374 hasConcept C37463918 @default.
- W1838893374 hasConcept C500558357 @default.
- W1838893374 hasConcept C54355233 @default.
- W1838893374 hasConcept C71924100 @default.
- W1838893374 hasConcept C84393581 @default.
- W1838893374 hasConcept C86803240 @default.
- W1838893374 hasConcept C90924648 @default.
- W1838893374 hasConcept C99454951 @default.
- W1838893374 hasConceptScore W1838893374C104317684 @default.
- W1838893374 hasConceptScore W1838893374C126322002 @default.
- W1838893374 hasConceptScore W1838893374C135763542 @default.
- W1838893374 hasConceptScore W1838893374C180754005 @default.
- W1838893374 hasConceptScore W1838893374C27016395 @default.
- W1838893374 hasConceptScore W1838893374C2778213512 @default.
- W1838893374 hasConceptScore W1838893374C2778817970 @default.
- W1838893374 hasConceptScore W1838893374C2908647359 @default.
- W1838893374 hasConceptScore W1838893374C31467283 @default.
- W1838893374 hasConceptScore W1838893374C37463918 @default.
- W1838893374 hasConceptScore W1838893374C500558357 @default.
- W1838893374 hasConceptScore W1838893374C54355233 @default.
- W1838893374 hasConceptScore W1838893374C71924100 @default.
- W1838893374 hasConceptScore W1838893374C84393581 @default.
- W1838893374 hasConceptScore W1838893374C86803240 @default.
- W1838893374 hasConceptScore W1838893374C90924648 @default.
- W1838893374 hasConceptScore W1838893374C99454951 @default.
- W1838893374 hasIssue "6" @default.
- W1838893374 hasLocation W18388933741 @default.
- W1838893374 hasLocation W18388933742 @default.
- W1838893374 hasOpenAccess W1838893374 @default.
- W1838893374 hasPrimaryLocation W18388933741 @default.
- W1838893374 hasRelatedWork W2004355765 @default.
- W1838893374 hasRelatedWork W2021855300 @default.
- W1838893374 hasRelatedWork W2051135531 @default.
- W1838893374 hasRelatedWork W2055888944 @default.
- W1838893374 hasRelatedWork W2065221218 @default.
- W1838893374 hasRelatedWork W2380813865 @default.
- W1838893374 hasRelatedWork W2810362112 @default.
- W1838893374 hasRelatedWork W2883538728 @default.
- W1838893374 hasRelatedWork W2972558724 @default.
- W1838893374 hasRelatedWork W3206047998 @default.
- W1838893374 hasVolume "58" @default.
- W1838893374 isParatext "false" @default.
- W1838893374 isRetracted "false" @default.
- W1838893374 magId "1838893374" @default.
- W1838893374 workType "article" @default.