FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1839003813> ?p ?o ?g. }

• W1839003813 endingPage "426" @default.
• W1839003813 startingPage "422" @default.
• W1839003813 abstract "The effect of human polymorphonuclear leukocytes (PMNs) on Chlamydia trachomatis was studied. Both trachoma (B/TW-5/OT) and lymphogranuloma venereum (L2/434/Bu) biotypes were rapidly inactivated by exposure to human PMNs. A decrease of 3 to 3.5 logs in viable count was observed after 60 min of incubation at a chlamydia-to-PMN ratio of 1:10. Both chlamydial biotypes were also rapidly inactivated by the cell-free myeloperoxidase-H2O2-halide system. A decrease in infectivity titer of 4 to 5 logs for TW-5 and complete inactivation of 434 were seen after 30 min of incubation. The microbicidal effect was prevented by the deletion of each component of the system or by the addition of the peroxidase inhibitors cyanide or azide. PMNs from myeloperoxidase-deficient patients inactivated chlamydiae normally, whereas PMNs from patients with chronic granulomatous disease, although strongly chlamydicidal, were less effective than normal PMNs in the activation of TW-5 (2-log drop in viable organisms versus a 3 to 3.5-log drop). The chlamydicidal activity of PMNs from patients with chronic granulomatous disease and normal PMNs were comparable against the 434 biotype. These studies suggest that the myeloperoxidase system, or indeed oxygen-dependent antimicrobial systems, are not essential for the chlamydicidal activity of PMNs." @default.
• W1839003813 created "2016-06-24" @default.
• W1839003813 creator A5054098403 @default.
• W1839003813 creator A5061806019 @default.
• W1839003813 creator A5071391179 @default.
• W1839003813 date "1982-08-01" @default.
• W1839003813 modified "2023-10-16" @default.
• W1839003813 title "Toxic effect of human polymorphonuclear leukocytes on Chlamydia trachomatis" @default.
• W1839003813 cites W109974505 @default.
• W1839003813 cites W1827383274 @default.
• W1839003813 cites W1972824411 @default.
• W1839003813 cites W1990083538 @default.
• W1839003813 cites W2014383612 @default.
• W1839003813 cites W2021422476 @default.
• W1839003813 cites W2028779046 @default.
• W1839003813 cites W2051273574 @default.
• W1839003813 cites W2074777134 @default.
• W1839003813 cites W2087106575 @default.
• W1839003813 cites W2096578491 @default.
• W1839003813 cites W2133541646 @default.
• W1839003813 cites W2159151572 @default.
• W1839003813 cites W2163260453 @default.
• W1839003813 cites W2165781084 @default.
• W1839003813 cites W2284702808 @default.
• W1839003813 cites W2288533488 @default.
• W1839003813 cites W2304387960 @default.
• W1839003813 cites W2334432250 @default.
• W1839003813 cites W4244209136 @default.
• W1839003813 cites W59833527 @default.
• W1839003813 doi "https://doi.org/10.1128/iai.37.2.422-426.1982" @default.
• W1839003813 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/347550" @default.
• W1839003813 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6288561" @default.
• W1839003813 hasPublicationYear "1982" @default.
• W1839003813 type Work @default.
• W1839003813 sameAs 1839003813 @default.
• W1839003813 citedByCount "56" @default.
• W1839003813 countsByYear W18390038132013 @default.
• W1839003813 countsByYear W18390038132014 @default.
• W1839003813 countsByYear W18390038132017 @default.
• W1839003813 countsByYear W18390038132019 @default.
• W1839003813 countsByYear W18390038132023 @default.
• W1839003813 crossrefType "journal-article" @default.
• W1839003813 hasAuthorship W1839003813A5054098403 @default.
• W1839003813 hasAuthorship W1839003813A5061806019 @default.
• W1839003813 hasAuthorship W1839003813A5071391179 @default.
• W1839003813 hasBestOaLocation W18390038131 @default.
• W1839003813 hasConcept C106358424 @default.
• W1839003813 hasConcept C160448771 @default.
• W1839003813 hasConcept C162008176 @default.
• W1839003813 hasConcept C181199279 @default.
• W1839003813 hasConcept C198677920 @default.
• W1839003813 hasConcept C203014093 @default.
• W1839003813 hasConcept C203565725 @default.
• W1839003813 hasConcept C2522874641 @default.
• W1839003813 hasConcept C25642318 @default.
• W1839003813 hasConcept C2776334974 @default.
• W1839003813 hasConcept C2776914184 @default.
• W1839003813 hasConcept C2777038808 @default.
• W1839003813 hasConcept C2777391075 @default.
• W1839003813 hasConcept C2777700362 @default.
• W1839003813 hasConcept C2777983669 @default.
• W1839003813 hasConcept C2778175462 @default.
• W1839003813 hasConcept C2779204014 @default.
• W1839003813 hasConcept C2780122209 @default.
• W1839003813 hasConcept C55493867 @default.
• W1839003813 hasConcept C86803240 @default.
• W1839003813 hasConcept C89423630 @default.
• W1839003813 hasConcept C99971728 @default.
• W1839003813 hasConceptScore W1839003813C106358424 @default.
• W1839003813 hasConceptScore W1839003813C160448771 @default.
• W1839003813 hasConceptScore W1839003813C162008176 @default.
• W1839003813 hasConceptScore W1839003813C181199279 @default.
• W1839003813 hasConceptScore W1839003813C198677920 @default.
• W1839003813 hasConceptScore W1839003813C203014093 @default.
• W1839003813 hasConceptScore W1839003813C203565725 @default.
• W1839003813 hasConceptScore W1839003813C2522874641 @default.
• W1839003813 hasConceptScore W1839003813C25642318 @default.
• W1839003813 hasConceptScore W1839003813C2776334974 @default.
• W1839003813 hasConceptScore W1839003813C2776914184 @default.
• W1839003813 hasConceptScore W1839003813C2777038808 @default.
• W1839003813 hasConceptScore W1839003813C2777391075 @default.
• W1839003813 hasConceptScore W1839003813C2777700362 @default.
• W1839003813 hasConceptScore W1839003813C2777983669 @default.
• W1839003813 hasConceptScore W1839003813C2778175462 @default.
• W1839003813 hasConceptScore W1839003813C2779204014 @default.
• W1839003813 hasConceptScore W1839003813C2780122209 @default.
• W1839003813 hasConceptScore W1839003813C55493867 @default.
• W1839003813 hasConceptScore W1839003813C86803240 @default.
• W1839003813 hasConceptScore W1839003813C89423630 @default.
• W1839003813 hasConceptScore W1839003813C99971728 @default.
• W1839003813 hasIssue "2" @default.
• W1839003813 hasLocation W18390038131 @default.
• W1839003813 hasLocation W18390038132 @default.
• W1839003813 hasLocation W18390038133 @default.
• W1839003813 hasOpenAccess W1839003813 @default.
• W1839003813 hasPrimaryLocation W18390038131 @default.
• W1839003813 hasRelatedWork W1147280289 @default.
• W1839003813 hasRelatedWork W158018095 @default.

• next