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• W1839562273 endingPage "373" @default.
• W1839562273 startingPage "343" @default.
• W1839562273 abstract "Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual influenza vaccination. Eighty older institutionalised patients suffering from dementia (54 women and 26 men) continuously wore an activity tracker for 8 weeks to assess individual light exposure and rest-activity cycles. We analysed the patients’ immune response from two blood samples taken before and 4 weeks after the annual influenza vaccination. Individual antibody concentrations to three influenza virus strains (H3N2, H1N1, IB) were quantified via hemagglutination inhibition assays. By quantifying individual light exposure profiles (including daylight), we classified the patients into a low and a high light exposure group based on a median illuminance of 392.6 lux. The two light exposure groups did not differ in cognitive impairment severity, age or gender distribution. However, patients in the high light exposure group showed a significantly greater circadian rest-activity amplitude (i.e., more daytime activity and less nighttime activity) along with a significantly greater antibody titer increase to the H3N2 vaccine than patients in the low light exposure group, despite similar pre-vaccination concentrations. Sufficient seroprotective responses to all three influenza virus strains were attained for ≥75% of participants. These data provide preliminary evidence for a potentially enhanced immune response in patients with dementia when they received more daily light. Future studies are needed to determine whether regular daily light exposure may have beneficial effects on the human immune system, either directly or via a stabilising circadian sleep-wake rhythms." @default.
• W1839562273 created "2016-06-24" @default.
• W1839562273 creator A5041129618 @default.
• W1839562273 creator A5052712397 @default.
• W1839562273 creator A5059042888 @default.
• W1839562273 creator A5062503784 @default.
• W1839562273 creator A5062699424 @default.
• W1839562273 creator A5088539070 @default.
• W1839562273 date "2002-01-01" @default.
• W1839562273 modified "2023-10-06" @default.
• W1839562273 title "Brain aging and Alzheimer's disease; use it or lose it" @default.
• W1839562273 cites W1532292616 @default.
• W1839562273 cites W1542215809 @default.
• W1839562273 cites W1584765072 @default.
• W1839562273 cites W1638939027 @default.
• W1839562273 cites W1768941645 @default.
• W1839562273 cites W1901043290 @default.
• W1839562273 cites W1913052892 @default.
• W1839562273 cites W1948740236 @default.
• W1839562273 cites W195908663 @default.
• W1839562273 cites W1964606698 @default.
• W1839562273 cites W1964697747 @default.
• W1839562273 cites W1965762855 @default.
• W1839562273 cites W1966014994 @default.
• W1839562273 cites W1966868909 @default.
• W1839562273 cites W1968892572 @default.
• W1839562273 cites W1970269823 @default.
• W1839562273 cites W1970601481 @default.
• W1839562273 cites W1971649076 @default.
• W1839562273 cites W1972009940 @default.
• W1839562273 cites W1973295647 @default.
• W1839562273 cites W1973531344 @default.
• W1839562273 cites W1974475508 @default.
• W1839562273 cites W1974607544 @default.
• W1839562273 cites W1975764592 @default.
• W1839562273 cites W1976124383 @default.
• W1839562273 cites W1977523725 @default.
• W1839562273 cites W1977638771 @default.
• W1839562273 cites W1977656398 @default.
• W1839562273 cites W1978119032 @default.
• W1839562273 cites W1980263164 @default.
• W1839562273 cites W1980490090 @default.
• W1839562273 cites W1981115828 @default.
• W1839562273 cites W1981190087 @default.
• W1839562273 cites W1981919520 @default.
• W1839562273 cites W1983558855 @default.
• W1839562273 cites W1983603578 @default.
• W1839562273 cites W1984827962 @default.
• W1839562273 cites W1985667235 @default.
• W1839562273 cites W1986260945 @default.
• W1839562273 cites W1986496873 @default.
• W1839562273 cites W1987301978 @default.
• W1839562273 cites W1987934133 @default.
• W1839562273 cites W1990752558 @default.
• W1839562273 cites W1991758365 @default.
• W1839562273 cites W1991969438 @default.
• W1839562273 cites W1992222048 @default.
• W1839562273 cites W1992433158 @default.
• W1839562273 cites W1992511388 @default.
• W1839562273 cites W1992841111 @default.
• W1839562273 cites W1994284320 @default.
• W1839562273 cites W1995785495 @default.
• W1839562273 cites W1995809230 @default.
• W1839562273 cites W1998390552 @default.
• W1839562273 cites W1999667056 @default.
• W1839562273 cites W1999976079 @default.
• W1839562273 cites W2004311396 @default.
• W1839562273 cites W2004543627 @default.
• W1839562273 cites W2005025961 @default.
• W1839562273 cites W2005994343 @default.
• W1839562273 cites W2007986024 @default.
• W1839562273 cites W2008350281 @default.
• W1839562273 cites W2009078449 @default.
• W1839562273 cites W2012391084 @default.
• W1839562273 cites W2012523260 @default.
• W1839562273 cites W2012620700 @default.
• W1839562273 cites W2013145243 @default.
• W1839562273 cites W2013486109 @default.
• W1839562273 cites W2014225927 @default.
• W1839562273 cites W2015795476 @default.
• W1839562273 cites W2016881921 @default.
• W1839562273 cites W2018041359 @default.
• W1839562273 cites W2018070696 @default.
• W1839562273 cites W2018638226 @default.
• W1839562273 cites W2018779032 @default.
• W1839562273 cites W2019319359 @default.
• W1839562273 cites W2020202552 @default.
• W1839562273 cites W2020229076 @default.
• W1839562273 cites W2020411164 @default.
• W1839562273 cites W2020453653 @default.
• W1839562273 cites W2020486984 @default.
• W1839562273 cites W2021134013 @default.
• W1839562273 cites W2021710511 @default.
• W1839562273 cites W2023121717 @default.
• W1839562273 cites W2023359029 @default.
• W1839562273 cites W2024310593 @default.
• W1839562273 cites W2024414157 @default.
• W1839562273 cites W2025014038 @default.

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