FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1840401327> ?p ?o ?g. }

• W1840401327 endingPage "15" @default.
• W1840401327 startingPage "409" @default.
• W1840401327 abstract "Up to 40% of patients with schizophrenic psychoses have symptoms that are resistant to monotherapy with antipsychotic drugs. In consequence, combinations of drugs are often used, especially based on the antipsychotic agents clozapine and olanzapine because of their broad receptor-interaction profile. The aim of this review was to provide a critical overview of the published results of olanzapine augmentation.A systematic database search was performed of MEDLINE and BIOSIS (Ovid), looking for publications on augmented therapeutic approaches involving olanzapine. The search terms used were augmentation, combination, schizophrenia, olanzapine, and the names of other antipsychotic drugs and non-antipsychotic agents, including brand names, spanning publications from 1966 until the end of December 2004.Of 14 reports dealing with 8 different antipsychotic augmentation strategies (83 patients), only 1 trial, of sulpiride-olanzapine therapy, was performed in a randomized manner. Based on clinical observation, a significant number of the treatments led to favourable results. In contrast to adjuvant therapy with antipsychotic drugs, augmentation of olanzapine with glycine, antidepressants or mood stabilizers was evaluated in well-designed clinical trials (8 publications, 989 patients), with distinct improvements of positive and/or negative symptoms reported.The combination of olanzapine with antidopaminergic atypical antipsychotic agents seems to follow a neurobiological rationale. The augmentation trials with non-antipsychotic agents, for example, mood stabilizers, were successful and showed that randomized and placebo-controlled trials are feasible. Therefore, systematic evaluations of antipsychotic agents as adjuvant therapy are possible as well as necessary to determine the benefits and risks of any new treatment strategy." @default.
• W1840401327 created "2016-06-24" @default.
• W1840401327 creator A5045679081 @default.
• W1840401327 date "2005-11-01" @default.
• W1840401327 modified "2023-09-23" @default.
• W1840401327 title "Augmentation of olanzapine in treatment-resistant schizophrenia." @default.
• W1840401327 cites W104921085 @default.
• W1840401327 cites W112226488 @default.
• W1840401327 cites W1572536584 @default.
• W1840401327 cites W1701339540 @default.
• W1840401327 cites W1720832074 @default.
• W1840401327 cites W175177365 @default.
• W1840401327 cites W1788388822 @default.
• W1840401327 cites W1904924604 @default.
• W1840401327 cites W1974910824 @default.
• W1840401327 cites W1975756063 @default.
• W1840401327 cites W1977313173 @default.
• W1840401327 cites W1978078779 @default.
• W1840401327 cites W1981477460 @default.
• W1840401327 cites W1983662592 @default.
• W1840401327 cites W1988849721 @default.
• W1840401327 cites W1992111439 @default.
• W1840401327 cites W1993737776 @default.
• W1840401327 cites W1994550766 @default.
• W1840401327 cites W1997544352 @default.
• W1840401327 cites W1998569841 @default.
• W1840401327 cites W2000966892 @default.
• W1840401327 cites W2001131550 @default.
• W1840401327 cites W2002013308 @default.
• W1840401327 cites W2003518980 @default.
• W1840401327 cites W2004770046 @default.
• W1840401327 cites W2010402674 @default.
• W1840401327 cites W2015308367 @default.
• W1840401327 cites W2015482820 @default.
• W1840401327 cites W2023797597 @default.
• W1840401327 cites W2027934187 @default.
• W1840401327 cites W2028744778 @default.
• W1840401327 cites W2029600226 @default.
• W1840401327 cites W2030393308 @default.
• W1840401327 cites W2035273224 @default.
• W1840401327 cites W2040934031 @default.
• W1840401327 cites W2041045231 @default.
• W1840401327 cites W2041862233 @default.
• W1840401327 cites W2042530149 @default.
• W1840401327 cites W2044297343 @default.
• W1840401327 cites W2050562983 @default.
• W1840401327 cites W2058147526 @default.
• W1840401327 cites W2060341782 @default.
• W1840401327 cites W2061451249 @default.
• W1840401327 cites W2067786055 @default.
• W1840401327 cites W2068898125 @default.
• W1840401327 cites W2077145937 @default.
• W1840401327 cites W2079510145 @default.
• W1840401327 cites W2085728163 @default.
• W1840401327 cites W2086678987 @default.
• W1840401327 cites W2093140608 @default.
• W1840401327 cites W2098102155 @default.
• W1840401327 cites W2106352416 @default.
• W1840401327 cites W2111355579 @default.
• W1840401327 cites W2119527374 @default.
• W1840401327 cites W2130535790 @default.
• W1840401327 cites W2142670205 @default.
• W1840401327 cites W2158108357 @default.
• W1840401327 cites W2160330420 @default.
• W1840401327 cites W2166158209 @default.
• W1840401327 cites W2167597323 @default.
• W1840401327 cites W2333441088 @default.
• W1840401327 cites W312142861 @default.
• W1840401327 cites W4211012484 @default.
• W1840401327 cites W59855775 @default.
• W1840401327 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1277023" @default.
• W1840401327 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16327874" @default.
• W1840401327 hasPublicationYear "2005" @default.
• W1840401327 type Work @default.
• W1840401327 sameAs 1840401327 @default.
• W1840401327 citedByCount "11" @default.
• W1840401327 countsByYear W18404013272014 @default.
• W1840401327 countsByYear W18404013272018 @default.
• W1840401327 countsByYear W18404013272019 @default.
• W1840401327 crossrefType "journal-article" @default.
• W1840401327 hasAuthorship W1840401327A5045679081 @default.
• W1840401327 hasConcept C118552586 @default.
• W1840401327 hasConcept C126322002 @default.
• W1840401327 hasConcept C142724271 @default.
• W1840401327 hasConcept C15744967 @default.
• W1840401327 hasConcept C168563851 @default.
• W1840401327 hasConcept C204787440 @default.
• W1840401327 hasConcept C27081682 @default.
• W1840401327 hasConcept C2775870346 @default.
• W1840401327 hasConcept C2776412080 @default.
• W1840401327 hasConcept C2776619155 @default.
• W1840401327 hasConcept C2776921671 @default.
• W1840401327 hasConcept C2780494398 @default.
• W1840401327 hasConcept C2780864610 @default.
• W1840401327 hasConcept C71924100 @default.
• W1840401327 hasConcept C98274493 @default.
• W1840401327 hasConceptScore W1840401327C118552586 @default.
• W1840401327 hasConceptScore W1840401327C126322002 @default.

• next