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• W1840585731 abstract "Abstract P element dysgenesis associated male recombination in Drosophila was examined with a selective system focused upon 5% of the standard female genetic map divided into eight recombination segments. We found no correspondence between P element mobilization events and recombination in males in the intervals monitored. We defined two adjacent short genetic and molecular regions, one devoid of male recombination and the other acting as a hot spot for exchange in the absence of supporting P element insertion and excision activity. These data suggest that, even in the presence of mobilizing P elements, transposase may be active at non-P element sites, and that the genome may harbor sequences ranging from highly responsive to completely unresponsive to transposase action. A viewpoint is presented wherein P elements, with sequences that bind transposase, serve to focus the recombination action of transposase to encompass a region of DNA radiating outward from the initial binding site. We suggest that this region is measured in terms of chromosomal segments rather than limited to P element sequences." @default.
• W1840585731 created "2016-06-24" @default.
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• W1840585731 date "1990-02-01" @default.
• W1840585731 modified "2023-10-18" @default.
• W1840585731 title "The relationship between P elements and male recombination in Drosophila melanogaster." @default.
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• W1840585731 doi "https://doi.org/10.1093/genetics/124.2.317" @default.
• W1840585731 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1203924" @default.
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• W1840585731 hasPublicationYear "1990" @default.
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