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- W1841060429 abstract "To compare the efficacy of Crinone 8% intravaginal progesterone gel vs. IM progesterone for luteal phase and early pregnancy support after IVF-ET.Randomized, open-label study.Academic medical center.Two hundred and one women undergoing IVF-ET.Women were randomized to supplementation with Crinone 8% (90 mg once daily) or IM progesterone (50 mg once daily) beginning the day after oocyte retrieval.Pregnancy, embryo implantation, and live birth rates.The women randomized to luteal phase supplementation with IM progesterone had significantly higher clinical pregnancy (48.5% vs. 30.4%; odds ratio [OR], 2.16; 95% confidence interval [CI], 1.21, 3.87), embryo implantation (24.1% vs. 17.5%; OR, 1.89; 95% CI, 1.08, 3.30), and live birth rates (39.4% vs. 24.5%; OR, 2.00; 95% CI, 1.10, 3.70) than women randomized to Crinone 8%.In women undergoing IVF-ET, once-a-day progesterone supplementation with Crinone 8%, beginning the day after oocyte retrieval, resulted in significantly lower embryo implantation, clinical pregnancy, and live birth rates compared with women supplemented with IM progesterone." @default.
- W1841060429 created "2016-06-24" @default.
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- W1841060429 date "2001-12-01" @default.
- W1841060429 modified "2023-10-02" @default.
- W1841060429 title "A randomized study comparing Crinone 8% and intramuscular progesterone supplementation in in vitro fertilization-embryo transfer cycles" @default.
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- W1841060429 doi "https://doi.org/10.1016/s0015-0282(01)02872-2" @default.
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