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• W1841712929 abstract "We reported previously that Notch signaling is activated in human arteriovenous malformations (AVMs) and that intracerebral hemorrhage (ICH) in humans is accompanied by increased neurogenesis. The former phenomenon may be involved in AVM pathogenesis and the latter in the brain’s response to ICH-induced injury. Here we describe increased expression of the hypoxia-inducible neuroprotective protein, neuroglobin (Ngb), in neurons surrounding unruptured AVMs and in the perihematomal region adjacent to ICH. In these disorders, as in other clinical settings, such as ischemic stroke, AVM- and ICH-induced overexpression of Ngb may be stimulated by ischemic hypoxia and may help to constrain brain injury." @default.
• W1841712929 created "2016-06-24" @default.
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• W1841712929 date "2011-01-01" @default.
• W1841712929 modified "2023-10-18" @default.
• W1841712929 title "Neuroglobin Expression in Human Arteriovenous Malformation and Intracerebral Hemorrhage" @default.
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• W1841712929 doi "https://doi.org/10.1007/978-3-7091-0693-8_52" @default.
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