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- W1842249900 startingPage "2083" @default.
- W1842249900 abstract "Similar features between the immune system of healthy elderly people and of younger individuals subjected to conditions of chronic immune activation are progressively being observed. This is raising the hypothesis that chronic immune activation may cause the premature aging of the immune system. Here we dissect this theory by comparing changes occurring to B-cells during healthy aging to the ones occurring during chronic immune activation in younger individuals. Moreover, we discuss how these changes may affect or predict response to vaccination in immune compromised individuals." @default.
- W1842249900 created "2016-06-24" @default.
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- W1842249900 date "2014-04-23" @default.
- W1842249900 modified "2023-09-30" @default.
- W1842249900 title "Premature B-cell senescence as a consequence of chronic immune activation" @default.
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- W1842249900 doi "https://doi.org/10.4161/hv.28698" @default.
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