FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1844026860> ?p ?o ?g. }

• W1844026860 endingPage "1104" @default.
• W1844026860 startingPage "1093" @default.
• W1844026860 abstract "TTF-1, a homeodomain-containing transcription factor, which is required for the specific expression of the thyroglobulin and thyroperoxidase gene promoters in differentiated thyroid cell lines, is expressed at the very beginning of rat thyroid differentiation. TTF-1 mRNA is detected in the endodermal cells of the thyroid rudiment in the rat embryo and precedes the expression of the two known target genes by 5 days. No delay is observed between the appearance of TTF-1 mRNA and protein, which shows a clear nuclear localization. In the adult thyroid, TTF-1 is present only in the endoderm-derived follicular cells. Two additional domains of expression of TTF-1 have been observed, the lung and restricted areas of the brain. In the lung, TTF-1 mRNA and protein are also present at the earliest stages of differentiation and are later confined to the bronchial epithelium. In the brain, TTF-1 appears to be restricted to structures of diencephalic origin, including the developing neurohypophysis. The early detection of TTF-1 in the endodermal cells of the thyroid and lung anlage and in restricted neuroblast populations indicates that TTF-1 may have a role in cell determination in these three systems and that additional mechanisms may be involved in the activation of thyroid-specific gene expression." @default.
• W1844026860 created "2016-06-24" @default.
• W1844026860 creator A5020772093 @default.
• W1844026860 creator A5029341507 @default.
• W1844026860 creator A5079652104 @default.
• W1844026860 creator A5084657559 @default.
• W1844026860 date "1991-12-01" @default.
• W1844026860 modified "2023-10-18" @default.
• W1844026860 title "The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain" @default.
• W1844026860 cites W106000010 @default.
• W1844026860 cites W1537876950 @default.
• W1844026860 cites W1767544560 @default.
• W1844026860 cites W1801375329 @default.
• W1844026860 cites W1882459971 @default.
• W1844026860 cites W1899130495 @default.
• W1844026860 cites W1912201670 @default.
• W1844026860 cites W1965455155 @default.
• W1844026860 cites W1970132032 @default.
• W1844026860 cites W1970521023 @default.
• W1844026860 cites W1971170993 @default.
• W1844026860 cites W1972354147 @default.
• W1844026860 cites W1984878154 @default.
• W1844026860 cites W1985126857 @default.
• W1844026860 cites W1986503880 @default.
• W1844026860 cites W1991439294 @default.
• W1844026860 cites W1996583872 @default.
• W1844026860 cites W1997130926 @default.
• W1844026860 cites W1997317042 @default.
• W1844026860 cites W2000612768 @default.
• W1844026860 cites W2002038171 @default.
• W1844026860 cites W2021861489 @default.
• W1844026860 cites W2022987966 @default.
• W1844026860 cites W2023660511 @default.
• W1844026860 cites W2025468425 @default.
• W1844026860 cites W2030904938 @default.
• W1844026860 cites W2040910893 @default.
• W1844026860 cites W2046541575 @default.
• W1844026860 cites W2051254858 @default.
• W1844026860 cites W2055310816 @default.
• W1844026860 cites W2057129205 @default.
• W1844026860 cites W2060708053 @default.
• W1844026860 cites W2062423659 @default.
• W1844026860 cites W2062617470 @default.
• W1844026860 cites W2064109349 @default.
• W1844026860 cites W2066379643 @default.
• W1844026860 cites W2067608765 @default.
• W1844026860 cites W2078348590 @default.
• W1844026860 cites W2091626902 @default.
• W1844026860 cites W2102113548 @default.
• W1844026860 cites W2141343816 @default.
• W1844026860 doi "https://doi.org/10.1242/dev.113.4.1093" @default.
• W1844026860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1811929" @default.
• W1844026860 hasPublicationYear "1991" @default.
• W1844026860 type Work @default.
• W1844026860 sameAs 1844026860 @default.
• W1844026860 citedByCount "810" @default.
• W1844026860 countsByYear W18440268602012 @default.
• W1844026860 countsByYear W18440268602013 @default.
• W1844026860 countsByYear W18440268602014 @default.
• W1844026860 countsByYear W18440268602015 @default.
• W1844026860 countsByYear W18440268602016 @default.
• W1844026860 countsByYear W18440268602017 @default.
• W1844026860 countsByYear W18440268602018 @default.
• W1844026860 countsByYear W18440268602019 @default.
• W1844026860 countsByYear W18440268602020 @default.
• W1844026860 countsByYear W18440268602021 @default.
• W1844026860 countsByYear W18440268602022 @default.
• W1844026860 countsByYear W18440268602023 @default.
• W1844026860 crossrefType "journal-article" @default.
• W1844026860 hasAuthorship W1844026860A5020772093 @default.
• W1844026860 hasAuthorship W1844026860A5029341507 @default.
• W1844026860 hasAuthorship W1844026860A5079652104 @default.
• W1844026860 hasAuthorship W1844026860A5084657559 @default.
• W1844026860 hasConcept C104317684 @default.
• W1844026860 hasConcept C121587040 @default.
• W1844026860 hasConcept C126322002 @default.
• W1844026860 hasConcept C134018914 @default.
• W1844026860 hasConcept C148738053 @default.
• W1844026860 hasConcept C2777164004 @default.
• W1844026860 hasConcept C2778835679 @default.
• W1844026860 hasConcept C2909723608 @default.
• W1844026860 hasConcept C39961270 @default.
• W1844026860 hasConcept C40692019 @default.
• W1844026860 hasConcept C4746552 @default.
• W1844026860 hasConcept C526584372 @default.
• W1844026860 hasConcept C54355233 @default.
• W1844026860 hasConcept C71924100 @default.
• W1844026860 hasConcept C86339819 @default.
• W1844026860 hasConcept C86803240 @default.
• W1844026860 hasConcept C95444343 @default.
• W1844026860 hasConceptScore W1844026860C104317684 @default.
• W1844026860 hasConceptScore W1844026860C121587040 @default.
• W1844026860 hasConceptScore W1844026860C126322002 @default.
• W1844026860 hasConceptScore W1844026860C134018914 @default.
• W1844026860 hasConceptScore W1844026860C148738053 @default.
• W1844026860 hasConceptScore W1844026860C2777164004 @default.
• W1844026860 hasConceptScore W1844026860C2778835679 @default.
• W1844026860 hasConceptScore W1844026860C2909723608 @default.

• next