Matches in SemOpenAlex for { <https://semopenalex.org/work/W1844135704> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W1844135704 endingPage "21" @default.
- W1844135704 startingPage "19" @default.
- W1844135704 abstract "To cite this article: Meno KH. Allergen structures and epitopes. Allergy 2011; 66 (Suppl. 95): 19–21. Abstract Human type 1 hypersensitivity diseases such as allergic rhinoconjunctivitis are characterized by allergen-specific IgE antibodies produced in allergic individuals after allergen exposure. IgE antibodies bound to receptors on the surface of effector cells trigger an allergic response by interacting with three-dimensional (conformational) epitopes on the allergen surface. Crystal structures are available for complexes of antibody specifically bound to five allergens, from birch pollen, bee venom, cockroach, cow’s milk and timothy grass pollen. The details of the antibody–allergen interaction extending all the way to atomic resolution are available from such complexes. In vitro investigations using recombinant monoclonal antibodies and human basophils show that binding affinity is a key to triggering the allergic response. Continued molecular characterization of antibody–allergen interactions is paving the way for the use of recombinant allergens in allergen-specific diagnosis and immunotherapy." @default.
- W1844135704 created "2016-06-24" @default.
- W1844135704 creator A5017567769 @default.
- W1844135704 date "2011-06-13" @default.
- W1844135704 modified "2023-09-24" @default.
- W1844135704 title "Allergen structures and epitopes" @default.
- W1844135704 cites W1780900583 @default.
- W1844135704 cites W1869212877 @default.
- W1844135704 cites W1969500662 @default.
- W1844135704 cites W2001803927 @default.
- W1844135704 cites W2093607407 @default.
- W1844135704 cites W2098419338 @default.
- W1844135704 cites W2108241262 @default.
- W1844135704 cites W2138554472 @default.
- W1844135704 doi "https://doi.org/10.1111/j.1398-9995.2011.02625.x" @default.
- W1844135704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21668845" @default.
- W1844135704 hasPublicationYear "2011" @default.
- W1844135704 type Work @default.
- W1844135704 sameAs 1844135704 @default.
- W1844135704 citedByCount "11" @default.
- W1844135704 countsByYear W18441357042012 @default.
- W1844135704 countsByYear W18441357042013 @default.
- W1844135704 countsByYear W18441357042015 @default.
- W1844135704 countsByYear W18441357042016 @default.
- W1844135704 countsByYear W18441357042017 @default.
- W1844135704 crossrefType "journal-article" @default.
- W1844135704 hasAuthorship W1844135704A5017567769 @default.
- W1844135704 hasConcept C104317684 @default.
- W1844135704 hasConcept C141105273 @default.
- W1844135704 hasConcept C159654299 @default.
- W1844135704 hasConcept C185592680 @default.
- W1844135704 hasConcept C195616568 @default.
- W1844135704 hasConcept C203014093 @default.
- W1844135704 hasConcept C207480886 @default.
- W1844135704 hasConcept C2780510475 @default.
- W1844135704 hasConcept C40767141 @default.
- W1844135704 hasConcept C542903549 @default.
- W1844135704 hasConcept C55493867 @default.
- W1844135704 hasConcept C71924100 @default.
- W1844135704 hasConceptScore W1844135704C104317684 @default.
- W1844135704 hasConceptScore W1844135704C141105273 @default.
- W1844135704 hasConceptScore W1844135704C159654299 @default.
- W1844135704 hasConceptScore W1844135704C185592680 @default.
- W1844135704 hasConceptScore W1844135704C195616568 @default.
- W1844135704 hasConceptScore W1844135704C203014093 @default.
- W1844135704 hasConceptScore W1844135704C207480886 @default.
- W1844135704 hasConceptScore W1844135704C2780510475 @default.
- W1844135704 hasConceptScore W1844135704C40767141 @default.
- W1844135704 hasConceptScore W1844135704C542903549 @default.
- W1844135704 hasConceptScore W1844135704C55493867 @default.
- W1844135704 hasConceptScore W1844135704C71924100 @default.
- W1844135704 hasLocation W18441357041 @default.
- W1844135704 hasLocation W18441357042 @default.
- W1844135704 hasOpenAccess W1844135704 @default.
- W1844135704 hasPrimaryLocation W18441357041 @default.
- W1844135704 hasRelatedWork W1986190391 @default.
- W1844135704 hasRelatedWork W1998274656 @default.
- W1844135704 hasRelatedWork W2012181161 @default.
- W1844135704 hasRelatedWork W2013794360 @default.
- W1844135704 hasRelatedWork W2019808322 @default.
- W1844135704 hasRelatedWork W2039736738 @default.
- W1844135704 hasRelatedWork W2077768935 @default.
- W1844135704 hasRelatedWork W2397347758 @default.
- W1844135704 hasRelatedWork W2783630444 @default.
- W1844135704 hasRelatedWork W4283364380 @default.
- W1844135704 hasVolume "66" @default.
- W1844135704 isParatext "false" @default.
- W1844135704 isRetracted "false" @default.
- W1844135704 magId "1844135704" @default.
- W1844135704 workType "article" @default.