Matches in SemOpenAlex for { <https://semopenalex.org/work/W1844298340> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1844298340 endingPage "432" @default.
- W1844298340 startingPage "424" @default.
- W1844298340 abstract "Further studies on the expression of the two aspartokinase activities in Bacillus bovis are presented. Aspartokinase I (previously shown to be inhibited and repressed by lysine) was found to be repressed by diaminopimelate in the wild-type strain. However, in a mutant unable to convert diaminopimelate to lysine, starvation for lysine resulted in an increase in aspartokinase I activity. Thus, lysine itself or an immediate metabolite was the true effector of repression. Aspartokinase II (previously shown to be inhibited by lysine plus threonine) was repressed by threonine. Studies with the parent strain and auxotrophs inidicated that only threonine or an immediate metabolite of threonine was involved in this repression. Methionine and isoleucine were not effectors of any of the detected aspartokinase activities. Apart from inhibition and repression controls, a third as yet undefined regulatory mechanism operated to decrease the levels of both aspartokinases as growth declined, even in mutants in which repression control was absent. In thiosine-resistant, lysine-excreting mutants with elevated levels of aspartokinase, the increase in activity could always be attributed to one enzyme or the other, never both. The existence of separate structural genes for each aspartokinase is therefore suggested." @default.
- W1844298340 created "2016-06-24" @default.
- W1844298340 creator A5059770618 @default.
- W1844298340 creator A5071083044 @default.
- W1844298340 creator A5073413709 @default.
- W1844298340 date "1980-05-01" @default.
- W1844298340 modified "2023-09-23" @default.
- W1844298340 title "Regulation of lysine- and lysine-plus-threonine-inhibitable aspartokinases in Bacillus brevis" @default.
- W1844298340 cites W1505399916 @default.
- W1844298340 cites W154207657 @default.
- W1844298340 cites W1559097830 @default.
- W1844298340 cites W1606166770 @default.
- W1844298340 cites W1825514585 @default.
- W1844298340 cites W1881793108 @default.
- W1844298340 cites W1980142589 @default.
- W1844298340 cites W1988666250 @default.
- W1844298340 cites W1998247911 @default.
- W1844298340 cites W2013908014 @default.
- W1844298340 cites W2019797347 @default.
- W1844298340 cites W2078373739 @default.
- W1844298340 cites W2340565589 @default.
- W1844298340 cites W4235067701 @default.
- W1844298340 doi "https://doi.org/10.1128/jb.142.2.424-432.1980" @default.
- W1844298340 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/293994" @default.
- W1844298340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6247320" @default.
- W1844298340 hasPublicationYear "1980" @default.
- W1844298340 type Work @default.
- W1844298340 sameAs 1844298340 @default.
- W1844298340 citedByCount "17" @default.
- W1844298340 countsByYear W18442983402012 @default.
- W1844298340 countsByYear W18442983402013 @default.
- W1844298340 countsByYear W18442983402014 @default.
- W1844298340 countsByYear W18442983402020 @default.
- W1844298340 crossrefType "journal-article" @default.
- W1844298340 hasAuthorship W1844298340A5059770618 @default.
- W1844298340 hasAuthorship W1844298340A5071083044 @default.
- W1844298340 hasAuthorship W1844298340A5073413709 @default.
- W1844298340 hasBestOaLocation W18442983401 @default.
- W1844298340 hasConcept C104317684 @default.
- W1844298340 hasConcept C143065580 @default.
- W1844298340 hasConcept C150194340 @default.
- W1844298340 hasConcept C181199279 @default.
- W1844298340 hasConcept C186310378 @default.
- W1844298340 hasConcept C2775880066 @default.
- W1844298340 hasConcept C2776016237 @default.
- W1844298340 hasConcept C2776414213 @default.
- W1844298340 hasConcept C2777477808 @default.
- W1844298340 hasConcept C2780912031 @default.
- W1844298340 hasConcept C2910736867 @default.
- W1844298340 hasConcept C515207424 @default.
- W1844298340 hasConcept C55493867 @default.
- W1844298340 hasConcept C86803240 @default.
- W1844298340 hasConceptScore W1844298340C104317684 @default.
- W1844298340 hasConceptScore W1844298340C143065580 @default.
- W1844298340 hasConceptScore W1844298340C150194340 @default.
- W1844298340 hasConceptScore W1844298340C181199279 @default.
- W1844298340 hasConceptScore W1844298340C186310378 @default.
- W1844298340 hasConceptScore W1844298340C2775880066 @default.
- W1844298340 hasConceptScore W1844298340C2776016237 @default.
- W1844298340 hasConceptScore W1844298340C2776414213 @default.
- W1844298340 hasConceptScore W1844298340C2777477808 @default.
- W1844298340 hasConceptScore W1844298340C2780912031 @default.
- W1844298340 hasConceptScore W1844298340C2910736867 @default.
- W1844298340 hasConceptScore W1844298340C515207424 @default.
- W1844298340 hasConceptScore W1844298340C55493867 @default.
- W1844298340 hasConceptScore W1844298340C86803240 @default.
- W1844298340 hasIssue "2" @default.
- W1844298340 hasLocation W18442983401 @default.
- W1844298340 hasLocation W18442983402 @default.
- W1844298340 hasLocation W18442983403 @default.
- W1844298340 hasOpenAccess W1844298340 @default.
- W1844298340 hasPrimaryLocation W18442983401 @default.
- W1844298340 hasRelatedWork W109353236 @default.
- W1844298340 hasRelatedWork W1980319026 @default.
- W1844298340 hasRelatedWork W2016542663 @default.
- W1844298340 hasRelatedWork W2081940762 @default.
- W1844298340 hasRelatedWork W2141508513 @default.
- W1844298340 hasRelatedWork W2152391841 @default.
- W1844298340 hasRelatedWork W2264111206 @default.
- W1844298340 hasRelatedWork W2565466705 @default.
- W1844298340 hasRelatedWork W2702647566 @default.
- W1844298340 hasRelatedWork W750301169 @default.
- W1844298340 hasVolume "142" @default.
- W1844298340 isParatext "false" @default.
- W1844298340 isRetracted "false" @default.
- W1844298340 magId "1844298340" @default.
- W1844298340 workType "article" @default.