FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1844439933> ?p ?o ?g. }

• W1844439933 endingPage "114" @default.
• W1844439933 startingPage "105" @default.
• W1844439933 abstract "Clostridium butyricum is a Gram-positive bacterium involved in the development of necrotizing enterocolitis (NEC) in preterm infants. To colonize the digestive tract, components of the cell wall of C. butyricum must interact with the intestinal mucosa. The d-alanylation of cell wall components such as teichoic acids results in a net positive charge on the cell wall, which is important for many functions of Gram-positive bacteria. Notably, d-alanylation mediates resistance to antimicrobial peptides and antibiotics. Here, we show that the dlt operon of C. butyricum encodes the enzymes responsible for the d-alanylation of cell wall components and influences the surface properties of the cell wall. We show that the d-alanylation of cell wall components controls the septation of C. butyricum, which is an essential mechanism during vegetative growth. Furthermore, we find that d-alanylation is involved in the resistance of C. butyricum to some cationic antimicrobial peptides (CAMPs) and lysozyme. Finally, we show that the d-alanylation of cell wall components influences vancomycin-induced lysis." @default.
• W1844439933 created "2016-06-24" @default.
• W1844439933 creator A5009156340 @default.
• W1844439933 creator A5009877383 @default.
• W1844439933 creator A5020813130 @default.
• W1844439933 creator A5022829588 @default.
• W1844439933 creator A5030260744 @default.
• W1844439933 creator A5031812767 @default.
• W1844439933 creator A5033840970 @default.
• W1844439933 date "2015-10-01" @default.
• W1844439933 modified "2023-09-30" @default.
• W1844439933 title "The functional dlt operon of Clostridium butyricum controls the d-alanylation of cell wall components and influences cell septation and vancomycin-induced lysis" @default.
• W1844439933 cites W146249449 @default.
• W1844439933 cites W1572509607 @default.
• W1844439933 cites W1958331559 @default.
• W1844439933 cites W1963563104 @default.
• W1844439933 cites W1965611861 @default.
• W1844439933 cites W1967799882 @default.
• W1844439933 cites W1971333632 @default.
• W1844439933 cites W1975704166 @default.
• W1844439933 cites W1976666632 @default.
• W1844439933 cites W1978227254 @default.
• W1844439933 cites W1980987268 @default.
• W1844439933 cites W1981025988 @default.
• W1844439933 cites W1984936173 @default.
• W1844439933 cites W1992444703 @default.
• W1844439933 cites W1996368063 @default.
• W1844439933 cites W2000426919 @default.
• W1844439933 cites W2009074972 @default.
• W1844439933 cites W2016451037 @default.
• W1844439933 cites W2019275072 @default.
• W1844439933 cites W2023964002 @default.
• W1844439933 cites W2035061442 @default.
• W1844439933 cites W2038231155 @default.
• W1844439933 cites W2043669567 @default.
• W1844439933 cites W2047522489 @default.
• W1844439933 cites W2049509412 @default.
• W1844439933 cites W2049812056 @default.
• W1844439933 cites W2067574120 @default.
• W1844439933 cites W2068010121 @default.
• W1844439933 cites W2069940309 @default.
• W1844439933 cites W2073623607 @default.
• W1844439933 cites W2076243547 @default.
• W1844439933 cites W2087965877 @default.
• W1844439933 cites W2096221995 @default.
• W1844439933 cites W2099047627 @default.
• W1844439933 cites W2102258368 @default.
• W1844439933 cites W2115200892 @default.
• W1844439933 cites W2119678266 @default.
• W1844439933 cites W2121857077 @default.
• W1844439933 cites W2122862073 @default.
• W1844439933 cites W2124988447 @default.
• W1844439933 cites W2125085985 @default.
• W1844439933 cites W2130534359 @default.
• W1844439933 cites W2130675566 @default.
• W1844439933 cites W2136051934 @default.
• W1844439933 cites W2140536580 @default.
• W1844439933 cites W2141676495 @default.
• W1844439933 cites W2143996485 @default.
• W1844439933 cites W2144948701 @default.
• W1844439933 cites W2152432564 @default.
• W1844439933 cites W2153244925 @default.
• W1844439933 cites W2162015645 @default.
• W1844439933 cites W2166410067 @default.
• W1844439933 cites W2292249423 @default.
• W1844439933 cites W4248759502 @default.
• W1844439933 doi "https://doi.org/10.1016/j.anaerobe.2015.09.001" @default.
• W1844439933 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26363197" @default.
• W1844439933 hasPublicationYear "2015" @default.
• W1844439933 type Work @default.
• W1844439933 sameAs 1844439933 @default.
• W1844439933 citedByCount "12" @default.
• W1844439933 countsByYear W18444399332017 @default.
• W1844439933 countsByYear W18444399332019 @default.
• W1844439933 countsByYear W18444399332020 @default.
• W1844439933 countsByYear W18444399332021 @default.
• W1844439933 countsByYear W18444399332023 @default.
• W1844439933 crossrefType "journal-article" @default.
• W1844439933 hasAuthorship W1844439933A5009156340 @default.
• W1844439933 hasAuthorship W1844439933A5009877383 @default.
• W1844439933 hasAuthorship W1844439933A5020813130 @default.
• W1844439933 hasAuthorship W1844439933A5022829588 @default.
• W1844439933 hasAuthorship W1844439933A5030260744 @default.
• W1844439933 hasAuthorship W1844439933A5031812767 @default.
• W1844439933 hasAuthorship W1844439933A5033840970 @default.
• W1844439933 hasConcept C125235067 @default.
• W1844439933 hasConcept C1491633281 @default.
• W1844439933 hasConcept C2776634448 @default.
• W1844439933 hasConcept C2777261523 @default.
• W1844439933 hasConcept C2778253522 @default.
• W1844439933 hasConcept C523546767 @default.
• W1844439933 hasConcept C54355233 @default.
• W1844439933 hasConcept C55493867 @default.
• W1844439933 hasConcept C57409179 @default.
• W1844439933 hasConcept C86803240 @default.
• W1844439933 hasConcept C89423630 @default.
• W1844439933 hasConceptScore W1844439933C125235067 @default.
• W1844439933 hasConceptScore W1844439933C1491633281 @default.

• next