Matches in SemOpenAlex for { <https://semopenalex.org/work/W1844658740> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1844658740 endingPage "4052" @default.
- W1844658740 startingPage "4046" @default.
- W1844658740 abstract "Abstract The gene for protein H, a novel bacterial cell wall protein with specific affinity for human IgG Fc, was cloned from a group A Streptococcus and expressed in Escherichia coli. Recombinant E. coli cells produced two forms of a human IgG Fc-binding protein, one with an apparent Mr of 42 kDa in a periplasmic fraction and the other with an apparent Mr of 45 kDa in a mixed fraction of cytoplasms and membranes. Both 42-kDa and 45-kDa protein preparations similarly bound to human IgG1 to IgG4, human IgG Fc, and rabbit IgG, but not to IgG of mouse, rat, bovine, sheep, goat, and human IgA, IgD, IgE, and IgM. The complete nucleotide sequence of the cloned 1.8-kb DNA fragment was determined. An open reading frame encoded a hypothetical protein of 376 amino acid residues (Mr = 42,498). The N-terminal amino acid sequence, consisting of 41 residues, which was removed post-translationally had typical characteristics of Gram-positive bacterial signal peptides. Thus, the mature form of protein H was suggested to consist of 335 residues (Mr = 38,162). There were 3 repeated sequences consisting of 42 residues that were highly homologous to those of protein Arp, an IgA-binding streptococcal cell wall protein, and streptococcal M6 and M24 proteins. The C-terminal amino acid sequence consisting of 93 residues, directly following the repeated sequences, was also highly homologous to that of M6 and M24 proteins. No sequence homology was found between protein H and protein A or protein G, two other IgG-binding bacterial cell wall proteins." @default.
- W1844658740 created "2016-06-24" @default.
- W1844658740 creator A5005892505 @default.
- W1844658740 creator A5032136556 @default.
- W1844658740 creator A5032803083 @default.
- W1844658740 creator A5046900640 @default.
- W1844658740 creator A5053324696 @default.
- W1844658740 creator A5073749409 @default.
- W1844658740 date "1990-05-15" @default.
- W1844658740 modified "2023-10-15" @default.
- W1844658740 title "The gene sequence and some properties of protein H. A novel IgG-binding protein." @default.
- W1844658740 doi "https://doi.org/10.4049/jimmunol.144.10.4046" @default.
- W1844658740 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2332638" @default.
- W1844658740 hasPublicationYear "1990" @default.
- W1844658740 type Work @default.
- W1844658740 sameAs 1844658740 @default.
- W1844658740 citedByCount "86" @default.
- W1844658740 countsByYear W18446587402012 @default.
- W1844658740 countsByYear W18446587402013 @default.
- W1844658740 countsByYear W18446587402014 @default.
- W1844658740 countsByYear W18446587402015 @default.
- W1844658740 countsByYear W18446587402016 @default.
- W1844658740 countsByYear W18446587402019 @default.
- W1844658740 countsByYear W18446587402021 @default.
- W1844658740 crossrefType "journal-article" @default.
- W1844658740 hasAuthorship W1844658740A5005892505 @default.
- W1844658740 hasAuthorship W1844658740A5032136556 @default.
- W1844658740 hasAuthorship W1844658740A5032803083 @default.
- W1844658740 hasAuthorship W1844658740A5046900640 @default.
- W1844658740 hasAuthorship W1844658740A5053324696 @default.
- W1844658740 hasAuthorship W1844658740A5073749409 @default.
- W1844658740 hasBestOaLocation W18446587401 @default.
- W1844658740 hasConcept C104317684 @default.
- W1844658740 hasConcept C116010114 @default.
- W1844658740 hasConcept C123894998 @default.
- W1844658740 hasConcept C135604509 @default.
- W1844658740 hasConcept C153911025 @default.
- W1844658740 hasConcept C159654299 @default.
- W1844658740 hasConcept C165525559 @default.
- W1844658740 hasConcept C167625842 @default.
- W1844658740 hasConcept C2778453870 @default.
- W1844658740 hasConcept C2779000548 @default.
- W1844658740 hasConcept C40767141 @default.
- W1844658740 hasConcept C48010095 @default.
- W1844658740 hasConcept C515207424 @default.
- W1844658740 hasConcept C54355233 @default.
- W1844658740 hasConcept C547475151 @default.
- W1844658740 hasConcept C553089730 @default.
- W1844658740 hasConcept C55493867 @default.
- W1844658740 hasConcept C84148353 @default.
- W1844658740 hasConcept C86803240 @default.
- W1844658740 hasConcept C88532467 @default.
- W1844658740 hasConceptScore W1844658740C104317684 @default.
- W1844658740 hasConceptScore W1844658740C116010114 @default.
- W1844658740 hasConceptScore W1844658740C123894998 @default.
- W1844658740 hasConceptScore W1844658740C135604509 @default.
- W1844658740 hasConceptScore W1844658740C153911025 @default.
- W1844658740 hasConceptScore W1844658740C159654299 @default.
- W1844658740 hasConceptScore W1844658740C165525559 @default.
- W1844658740 hasConceptScore W1844658740C167625842 @default.
- W1844658740 hasConceptScore W1844658740C2778453870 @default.
- W1844658740 hasConceptScore W1844658740C2779000548 @default.
- W1844658740 hasConceptScore W1844658740C40767141 @default.
- W1844658740 hasConceptScore W1844658740C48010095 @default.
- W1844658740 hasConceptScore W1844658740C515207424 @default.
- W1844658740 hasConceptScore W1844658740C54355233 @default.
- W1844658740 hasConceptScore W1844658740C547475151 @default.
- W1844658740 hasConceptScore W1844658740C553089730 @default.
- W1844658740 hasConceptScore W1844658740C55493867 @default.
- W1844658740 hasConceptScore W1844658740C84148353 @default.
- W1844658740 hasConceptScore W1844658740C86803240 @default.
- W1844658740 hasConceptScore W1844658740C88532467 @default.
- W1844658740 hasIssue "10" @default.
- W1844658740 hasLocation W18446587401 @default.
- W1844658740 hasLocation W18446587402 @default.
- W1844658740 hasOpenAccess W1844658740 @default.
- W1844658740 hasPrimaryLocation W18446587401 @default.
- W1844658740 hasRelatedWork W1983750488 @default.
- W1844658740 hasRelatedWork W1986699632 @default.
- W1844658740 hasRelatedWork W2005771319 @default.
- W1844658740 hasRelatedWork W2015187382 @default.
- W1844658740 hasRelatedWork W2015776603 @default.
- W1844658740 hasRelatedWork W2020859835 @default.
- W1844658740 hasRelatedWork W2077546600 @default.
- W1844658740 hasRelatedWork W2491994917 @default.
- W1844658740 hasRelatedWork W4205491143 @default.
- W1844658740 hasRelatedWork W4255866313 @default.
- W1844658740 hasVolume "144" @default.
- W1844658740 isParatext "false" @default.
- W1844658740 isRetracted "false" @default.
- W1844658740 magId "1844658740" @default.
- W1844658740 workType "article" @default.