FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W184485255> ?p ?o ?g. }

• W184485255 endingPage "295" @default.
• W184485255 startingPage "277" @default.
• W184485255 abstract "To compare different method(s) to detect peripheral neuropathy in leprosy and to study the validity of the monofilament test (MF) and the voluntary muscle test (VMT) as standard tests of nerve function.A multi-centre cohort study of 303 multibacillary (MB) leprosy patients.Newly registered MB patients requiring a full course of MDT were recruited in two leprosy outpatient clinics in North India. Controls were people without leprosy or neurological conditions, attending the dermatological outpatient departments of the same clinics. Nerve function was evaluated electrophysiologically using standard parameters for sensory and motor nerve conduction (NC) testing, warm and cold detection thresholds (W/CDT), vibration perception thresholds, dynamometry, MF and VMT. The latter two defined the outcomes of sensory and motor impairment.115 patients had nerve damage or a reaction of recent onset at diagnosis. Sensory and motor amplitudes and WDTs were the most frequently abnormal. Among the nerves tested, the sural and posterior tibial were the most frequently impaired. In the ulnar nerve, sensory latencies were abnormal in 25% of subjects; amplitudes in 40%. Ulnar above-elbow motor conduction velocities were abnormal in 39% and amplitudes 32%. WDTs were much more frequently affected than CDTs in all nerves tested. The thresholds of all test parameters differed significantly between controls and patients, while only some differed between patients with and without reaction. Good concordance was observed between MF results and sensory latencies and velocities (direct concordance 80% for the ulnar). However, a proportion of nerves with abnormal MF results tested normal on one or more of the other tests or vice versa. Concordance between VMT and motor conduction velocities was good for the ulnar nerve, but for the median and peroneal nerves, the proportion impaired by VMT out of those with abnormal motor conduction was very low.Concordance between monofilaments and other sensory function test results was good, supporting the validity of the monofilaments as standard screening test of sensory function. Concordance between VMT results and motor nerve conduction was good for the ulnar nerve, but very few median and peroneal nerves with abnormal conduction had an abnormal VMT. A more sensitive manual motor test may be needed for these nerves. Of the nerve assessment tests conducted, NC amplitudes and warm sensation were the most frequently affected. Therefore, nerve conduction studies and WDT measurements appear to be most promising tests for early detection of leprous neuropathy. The pattern of concordance between tactile and thermal sensory impairment failed to support the hypothesis that small fibre neuropathy always precedes large fibre damage. Warm sensation was more frequently affected than cold sensation. This could indicate that unmyelinated C fibres are more frequently affected than small myelinated Asigma fibres." @default.
• W184485255 created "2016-06-24" @default.
• W184485255 creator A5007115319 @default.
• W184485255 creator A5019338156 @default.
• W184485255 creator A5042870699 @default.
• W184485255 creator A5060491690 @default.
• W184485255 creator A5072003941 @default.
• W184485255 creator A5074429698 @default.
• W184485255 creator A5082007863 @default.
• W184485255 date "2005-12-01" @default.
• W184485255 modified "2023-10-18" @default.
• W184485255 title "The INFIR Cohort Study: assessment of sensory and motor neuropathy in leprosy at baseline" @default.
• W184485255 cites W1482217310 @default.
• W184485255 cites W152566216 @default.
• W184485255 cites W1756065261 @default.
• W184485255 cites W1770488833 @default.
• W184485255 cites W1892539883 @default.
• W184485255 cites W1965126871 @default.
• W184485255 cites W1971551330 @default.
• W184485255 cites W1974738766 @default.
• W184485255 cites W1981380552 @default.
• W184485255 cites W1985964144 @default.
• W184485255 cites W2009072190 @default.
• W184485255 cites W2013410636 @default.
• W184485255 cites W2014648797 @default.
• W184485255 cites W2019546868 @default.
• W184485255 cites W2020121076 @default.
• W184485255 cites W2024565707 @default.
• W184485255 cites W2025735041 @default.
• W184485255 cites W2040002256 @default.
• W184485255 cites W2040233885 @default.
• W184485255 cites W2052938970 @default.
• W184485255 cites W2053108155 @default.
• W184485255 cites W2059243367 @default.
• W184485255 cites W2076472923 @default.
• W184485255 cites W2081709175 @default.
• W184485255 cites W2118202495 @default.
• W184485255 cites W2127219183 @default.
• W184485255 cites W214575565 @default.
• W184485255 cites W2166861568 @default.
• W184485255 cites W2231216999 @default.
• W184485255 cites W2234625571 @default.
• W184485255 cites W2268431428 @default.
• W184485255 cites W2274312710 @default.
• W184485255 cites W2394941623 @default.
• W184485255 cites W2395355374 @default.
• W184485255 cites W2401019148 @default.
• W184485255 cites W2404144724 @default.
• W184485255 cites W2406467067 @default.
• W184485255 cites W2409067533 @default.
• W184485255 cites W2409919812 @default.
• W184485255 cites W2412609729 @default.
• W184485255 cites W2413214999 @default.
• W184485255 cites W2413346970 @default.
• W184485255 cites W2414351710 @default.
• W184485255 cites W2414766951 @default.
• W184485255 cites W2417775399 @default.
• W184485255 cites W2418375108 @default.
• W184485255 cites W2418376963 @default.
• W184485255 cites W2419594648 @default.
• W184485255 cites W2429350247 @default.
• W184485255 cites W2463019949 @default.
• W184485255 cites W2466492929 @default.
• W184485255 cites W2484294239 @default.
• W184485255 cites W2797597138 @default.
• W184485255 cites W71967333 @default.
• W184485255 cites W1465314767 @default.
• W184485255 cites W2092780614 @default.
• W184485255 cites W2403458316 @default.
• W184485255 doi "https://doi.org/10.47276/lr.76.4.277" @default.
• W184485255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16411508" @default.
• W184485255 hasPublicationYear "2005" @default.
• W184485255 type Work @default.
• W184485255 sameAs 184485255 @default.
• W184485255 citedByCount "64" @default.
• W184485255 countsByYear W1844852552012 @default.
• W184485255 countsByYear W1844852552013 @default.
• W184485255 countsByYear W1844852552014 @default.
• W184485255 countsByYear W1844852552015 @default.
• W184485255 countsByYear W1844852552016 @default.
• W184485255 countsByYear W1844852552017 @default.
• W184485255 countsByYear W1844852552019 @default.
• W184485255 countsByYear W1844852552020 @default.
• W184485255 countsByYear W1844852552021 @default.
• W184485255 countsByYear W1844852552022 @default.
• W184485255 countsByYear W1844852552023 @default.
• W184485255 crossrefType "journal-article" @default.
• W184485255 hasAuthorship W184485255A5007115319 @default.
• W184485255 hasAuthorship W184485255A5019338156 @default.
• W184485255 hasAuthorship W184485255A5042870699 @default.
• W184485255 hasAuthorship W184485255A5060491690 @default.
• W184485255 hasAuthorship W184485255A5072003941 @default.
• W184485255 hasAuthorship W184485255A5074429698 @default.
• W184485255 hasAuthorship W184485255A5082007863 @default.
• W184485255 hasBestOaLocation W1844852551 @default.
• W184485255 hasConcept C110235638 @default.
• W184485255 hasConcept C126322002 @default.
• W184485255 hasConcept C134018914 @default.

• next