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- W1844867070 abstract "Colorectal cancer (CRC) remains one of the major causes of death worldwide, despite steady improvement in early detection and overall survival over the past decade. Current treatment paradigms, with chemotherapy and biologics, appear to have reached their maximum benefit. Immunotherapy, especially with checkpoint inhibitors, has shown considerable clinical benefit in various cancers, including mismatch-repair-deficient CRC. This has led to the planning and initiation of several clinical trials evaluating novel immunotherapy agents-as single agents, combinations and in conjunction with chemotherapy-in patients with CRC. This article reviews biological and preclinical data for checkpoint inhibitors and discusses various immunotherapy trials in CRC, as well as current efforts in CRC immunotherapy." @default.
- W1844867070 created "2016-06-24" @default.
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- W1844867070 date "2015-10-27" @default.
- W1844867070 modified "2023-10-01" @default.
- W1844867070 title "Immune checkpoints and immunotherapy for colorectal cancer" @default.
- W1844867070 cites W1504535992 @default.
- W1844867070 cites W1581904411 @default.
- W1844867070 cites W1785873212 @default.
- W1844867070 cites W1809627231 @default.
- W1844867070 cites W1829526068 @default.
- W1844867070 cites W1940241680 @default.
- W1844867070 cites W1940904684 @default.
- W1844867070 cites W1970343639 @default.
- W1844867070 cites W1976171528 @default.
- W1844867070 cites W1976945431 @default.
- W1844867070 cites W1983143892 @default.
- W1844867070 cites W1984642649 @default.
- W1844867070 cites W1987625640 @default.
- W1844867070 cites W1988474688 @default.
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- W1844867070 cites W2015085911 @default.
- W1844867070 cites W2016983859 @default.
- W1844867070 cites W2018710900 @default.
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- W1844867070 cites W2052727153 @default.
- W1844867070 cites W2056535502 @default.
- W1844867070 cites W2060094878 @default.
- W1844867070 cites W2062173928 @default.
- W1844867070 cites W2065544364 @default.
- W1844867070 cites W2066964346 @default.
- W1844867070 cites W2068286936 @default.
- W1844867070 cites W2081534970 @default.
- W1844867070 cites W2087751238 @default.
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- W1844867070 cites W2154171512 @default.
- W1844867070 cites W2156353875 @default.
- W1844867070 cites W2157824068 @default.
- W1844867070 cites W2160834915 @default.
- W1844867070 cites W2161817637 @default.
- W1844867070 cites W2162889226 @default.
- W1844867070 cites W2164603058 @default.
- W1844867070 cites W2166026289 @default.
- W1844867070 cites W2170055192 @default.
- W1844867070 cites W2171190137 @default.
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- W1844867070 doi "https://doi.org/10.1093/gastro/gov053" @default.
- W1844867070 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4650981" @default.
- W1844867070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26510455" @default.
- W1844867070 hasPublicationYear "2015" @default.
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