Matches in SemOpenAlex for { <https://semopenalex.org/work/W1845254015> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1845254015 endingPage "3449" @default.
- W1845254015 startingPage "3442" @default.
- W1845254015 abstract "The proliferative response of PBMC to hepatitis B virus (HBV) envelope, core, and e Ag was analyzed prospectively in 21 patients with acute self-limited HBV infection and compared with the response of patients with chronic HBV infection and different levels of HBV replication (i.e., hepatitis e Ag (HBeAg)- or anti-HBe-positive) and liver damage (i.e., chronic active hepatitis or chronic asymptomatic carriers). Our results indicate that: 1) HBV-infected subjects who develop a self-limited acute hepatitis show a vigorous PBMC response to hepatitis B core Ag and HBeAg, as expression of T cell activation; 2) appearance of a detectable lymphocyte response to HBV nucleocapsid Ag is temporally associated with the clearance of HBV envelope Ag; 3) in patients with chronic HBV infection the level of T cell responsiveness to hepatitis B core Ag and to HBeAg is significantly lower than that observed during acute infection; 4) T cell sensitization to HBV envelope Ag in acute and chronic HBV infection is usually undetectable and when measurable is expressed transiently and at low levels. These results may reflect immune events of pathogenetic relevance with respect to evolution of disease and viral clearance." @default.
- W1845254015 created "2016-06-24" @default.
- W1845254015 creator A5005565231 @default.
- W1845254015 creator A5015328811 @default.
- W1845254015 creator A5023189240 @default.
- W1845254015 creator A5031164159 @default.
- W1845254015 creator A5039286311 @default.
- W1845254015 creator A5044038656 @default.
- W1845254015 creator A5053512278 @default.
- W1845254015 creator A5070463166 @default.
- W1845254015 creator A5083332602 @default.
- W1845254015 date "1990-11-15" @default.
- W1845254015 modified "2023-10-10" @default.
- W1845254015 title "Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection." @default.
- W1845254015 doi "https://doi.org/10.4049/jimmunol.145.10.3442" @default.
- W1845254015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2230128" @default.
- W1845254015 hasPublicationYear "1990" @default.
- W1845254015 type Work @default.
- W1845254015 sameAs 1845254015 @default.
- W1845254015 citedByCount "340" @default.
- W1845254015 countsByYear W18452540152012 @default.
- W1845254015 countsByYear W18452540152013 @default.
- W1845254015 countsByYear W18452540152014 @default.
- W1845254015 countsByYear W18452540152015 @default.
- W1845254015 countsByYear W18452540152016 @default.
- W1845254015 countsByYear W18452540152017 @default.
- W1845254015 countsByYear W18452540152018 @default.
- W1845254015 countsByYear W18452540152019 @default.
- W1845254015 countsByYear W18452540152020 @default.
- W1845254015 countsByYear W18452540152021 @default.
- W1845254015 countsByYear W18452540152022 @default.
- W1845254015 countsByYear W18452540152023 @default.
- W1845254015 crossrefType "journal-article" @default.
- W1845254015 hasAuthorship W1845254015A5005565231 @default.
- W1845254015 hasAuthorship W1845254015A5015328811 @default.
- W1845254015 hasAuthorship W1845254015A5023189240 @default.
- W1845254015 hasAuthorship W1845254015A5031164159 @default.
- W1845254015 hasAuthorship W1845254015A5039286311 @default.
- W1845254015 hasAuthorship W1845254015A5044038656 @default.
- W1845254015 hasAuthorship W1845254015A5053512278 @default.
- W1845254015 hasAuthorship W1845254015A5070463166 @default.
- W1845254015 hasAuthorship W1845254015A5083332602 @default.
- W1845254015 hasConcept C126322002 @default.
- W1845254015 hasConcept C137916694 @default.
- W1845254015 hasConcept C147483822 @default.
- W1845254015 hasConcept C159047783 @default.
- W1845254015 hasConcept C203014093 @default.
- W1845254015 hasConcept C2522874641 @default.
- W1845254015 hasConcept C2775940106 @default.
- W1845254015 hasConcept C2777382497 @default.
- W1845254015 hasConcept C2777410769 @default.
- W1845254015 hasConcept C2777910003 @default.
- W1845254015 hasConcept C2780593183 @default.
- W1845254015 hasConcept C2780617729 @default.
- W1845254015 hasConcept C71924100 @default.
- W1845254015 hasConcept C8891405 @default.
- W1845254015 hasConceptScore W1845254015C126322002 @default.
- W1845254015 hasConceptScore W1845254015C137916694 @default.
- W1845254015 hasConceptScore W1845254015C147483822 @default.
- W1845254015 hasConceptScore W1845254015C159047783 @default.
- W1845254015 hasConceptScore W1845254015C203014093 @default.
- W1845254015 hasConceptScore W1845254015C2522874641 @default.
- W1845254015 hasConceptScore W1845254015C2775940106 @default.
- W1845254015 hasConceptScore W1845254015C2777382497 @default.
- W1845254015 hasConceptScore W1845254015C2777410769 @default.
- W1845254015 hasConceptScore W1845254015C2777910003 @default.
- W1845254015 hasConceptScore W1845254015C2780593183 @default.
- W1845254015 hasConceptScore W1845254015C2780617729 @default.
- W1845254015 hasConceptScore W1845254015C71924100 @default.
- W1845254015 hasConceptScore W1845254015C8891405 @default.
- W1845254015 hasIssue "10" @default.
- W1845254015 hasLocation W18452540151 @default.
- W1845254015 hasLocation W18452540152 @default.
- W1845254015 hasOpenAccess W1845254015 @default.
- W1845254015 hasPrimaryLocation W18452540151 @default.
- W1845254015 hasRelatedWork W1494523999 @default.
- W1845254015 hasRelatedWork W1965983990 @default.
- W1845254015 hasRelatedWork W2001434381 @default.
- W1845254015 hasRelatedWork W2036869535 @default.
- W1845254015 hasRelatedWork W2064720744 @default.
- W1845254015 hasRelatedWork W2095853007 @default.
- W1845254015 hasRelatedWork W2132012395 @default.
- W1845254015 hasRelatedWork W2145782156 @default.
- W1845254015 hasRelatedWork W2170511845 @default.
- W1845254015 hasRelatedWork W2291166135 @default.
- W1845254015 hasVolume "145" @default.
- W1845254015 isParatext "false" @default.
- W1845254015 isRetracted "false" @default.
- W1845254015 magId "1845254015" @default.
- W1845254015 workType "article" @default.