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- W184562149 abstract "Nutritional research in relation to aging can be divided into two categories: research aimed at determining the nutritional needs of the elderly so that they may lead a relatively productive existence until the end of their lives and research concerned with extending the maximal lifespan of a group of people through nutritional means. This chapter illustrates the use of animal models in both types of research. There are two major criteria for selecting an animal model for aging research: (1) the similarity of the animal's aging characteristics to that of man's and (2) a sufficiently short lifespan to allow for replicate studies during an investigator's lifetime. The third possible criterion is that the animal's lifespan be less than the duration of the average research grant. The chapter also discusses changes in calcium absorption with age. Decreased absorption play a role in the development of osteomalacia and osteoporosis, two bone diseases that affect a large percentage of the older female population. The chapter also presents the effects of dietary restriction on maximum lifespan of animals and their physiological functions. Animal studies have shown that iron absorption may be improved by certain amino acids and sugars. Therefore, it may be possible to improve iron absorption in the elderly by feeding foods that increase the absorption of dietary iron." @default.
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- W184562149 date "1983-01-01" @default.
- W184562149 modified "2023-09-27" @default.
- W184562149 title "Animal Models in Aging Research" @default.
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- W184562149 doi "https://doi.org/10.1016/b978-0-7236-7046-9.50009-6" @default.
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