FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1845621716> ?p ?o ?g. }

• W1845621716 endingPage "339" @default.
• W1845621716 startingPage "328" @default.
• W1845621716 abstract "Intracellular components must be recycled for cells to maintain energy and ensure quality control of proteins and organelles. Autophagy is a highly conserved recycling process that involves degradation of cellular constituents in lysosomes. Although autophagy regulates a number of cell functions, it was first found to maintain energy balance in liver cells. As our understanding of autophagy has increased, we have found its connections to energy regulation in liver cells to be tight and complex. We review 3 mechanisms by which hepatic autophagy monitors and regulates cellular metabolism. Autophagy provides essential components (amino acids, lipids, and carbohydrates) required to meet the cell's energy needs, and it also regulates energy supply by controlling the number, quality, and dynamics of the mitochondria. Finally, autophagy also modulates levels of enzymes in metabolic pathways. In light of the multiple ways in which autophagy participates to control liver metabolism, it is no surprise that dysregulation of autophagy has been associated with metabolic diseases such as obesity, diabetes, or metabolic syndrome, as well as liver-specific disorders such as fatty liver, nonalcoholic steatohepatitis, and hepatocellular carcinoma. We discuss some of these connections and how hepatic autophagy might serve as a therapeutic target in common metabolic disorders." @default.
• W1845621716 created "2016-06-24" @default.
• W1845621716 creator A5063410689 @default.
• W1845621716 creator A5073096633 @default.
• W1845621716 date "2016-02-01" @default.
• W1845621716 modified "2023-10-17" @default.
• W1845621716 title "Regulation of Liver Metabolism by Autophagy" @default.
• W1845621716 cites W1523693806 @default.
• W1845621716 cites W1706150252 @default.
• W1845621716 cites W1741531311 @default.
• W1845621716 cites W1786920819 @default.
• W1845621716 cites W1847698873 @default.
• W1845621716 cites W1966132436 @default.
• W1845621716 cites W1968665833 @default.
• W1845621716 cites W1971554083 @default.
• W1845621716 cites W1975200363 @default.
• W1845621716 cites W1981950106 @default.
• W1845621716 cites W1982397114 @default.
• W1845621716 cites W1983049322 @default.
• W1845621716 cites W1985538633 @default.
• W1845621716 cites W1987467930 @default.
• W1845621716 cites W1991700908 @default.
• W1845621716 cites W1992659717 @default.
• W1845621716 cites W1993458861 @default.
• W1845621716 cites W1994823455 @default.
• W1845621716 cites W1995873922 @default.
• W1845621716 cites W1998560601 @default.
• W1845621716 cites W2004325124 @default.
• W1845621716 cites W2005064136 @default.
• W1845621716 cites W2005270729 @default.
• W1845621716 cites W2007505836 @default.
• W1845621716 cites W2007743440 @default.
• W1845621716 cites W2012600855 @default.
• W1845621716 cites W2014086521 @default.
• W1845621716 cites W2015207840 @default.
• W1845621716 cites W2015589839 @default.
• W1845621716 cites W2017948700 @default.
• W1845621716 cites W2021919397 @default.
• W1845621716 cites W2022716167 @default.
• W1845621716 cites W2022964430 @default.
• W1845621716 cites W2023338943 @default.
• W1845621716 cites W2026531364 @default.
• W1845621716 cites W2030430693 @default.
• W1845621716 cites W2033212418 @default.
• W1845621716 cites W2035444573 @default.
• W1845621716 cites W2044621729 @default.
• W1845621716 cites W2045122835 @default.
• W1845621716 cites W2046074477 @default.
• W1845621716 cites W2046447620 @default.
• W1845621716 cites W2049298036 @default.
• W1845621716 cites W2051429808 @default.
• W1845621716 cites W2051736114 @default.
• W1845621716 cites W2053493267 @default.
• W1845621716 cites W2054125361 @default.
• W1845621716 cites W2056664023 @default.
• W1845621716 cites W2058250395 @default.
• W1845621716 cites W2058498754 @default.
• W1845621716 cites W2060399754 @default.
• W1845621716 cites W2063920469 @default.
• W1845621716 cites W2066662062 @default.
• W1845621716 cites W2067636508 @default.
• W1845621716 cites W2068231534 @default.
• W1845621716 cites W2070871404 @default.
• W1845621716 cites W2072188665 @default.
• W1845621716 cites W2073956836 @default.
• W1845621716 cites W2076451416 @default.
• W1845621716 cites W2077757969 @default.
• W1845621716 cites W2078253583 @default.
• W1845621716 cites W2078881478 @default.
• W1845621716 cites W2079569342 @default.
• W1845621716 cites W2079801171 @default.
• W1845621716 cites W2082425146 @default.
• W1845621716 cites W2082476985 @default.
• W1845621716 cites W2089551665 @default.
• W1845621716 cites W2096348285 @default.
• W1845621716 cites W2096661568 @default.
• W1845621716 cites W2097799342 @default.
• W1845621716 cites W2099538852 @default.
• W1845621716 cites W2099841137 @default.
• W1845621716 cites W2103659405 @default.
• W1845621716 cites W2112668580 @default.
• W1845621716 cites W2116836791 @default.
• W1845621716 cites W2117695104 @default.
• W1845621716 cites W2121077787 @default.
• W1845621716 cites W2126037064 @default.
• W1845621716 cites W2132187946 @default.
• W1845621716 cites W2135714813 @default.
• W1845621716 cites W2136000647 @default.
• W1845621716 cites W2143070222 @default.
• W1845621716 cites W2146887271 @default.
• W1845621716 cites W2146961420 @default.
• W1845621716 cites W2150168624 @default.
• W1845621716 cites W2150418491 @default.
• W1845621716 cites W2153188271 @default.
• W1845621716 cites W2168445378 @default.
• W1845621716 cites W2169903226 @default.
• W1845621716 cites W2410924893 @default.
• W1845621716 doi "https://doi.org/10.1053/j.gastro.2015.09.042" @default.

• next