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- W1846490335 abstract "Protein phosphorylation is as general a mechanism as allosteric regulation, and usually the key regulatory enzyme in a pathway is subject to both types of control. Allosteric regulation is the mechanism by which the pathway responds to purely local changes in metabolite levels. This chapter discusses the scope and importance of protein phosphorylation in metabolism. The chapter also describes the experimental criteria, which should be met to establish the role of reversible phosphorylation in a particular regulatory system. It describes the techniques that may be used, and also some of the problems that may be encountered. The discussion is illustrated with examples drawn mainly from the regulation of fatty acid synthesis." @default.
- W1846490335 created "2016-06-24" @default.
- W1846490335 creator A5026057711 @default.
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- W1846490335 date "1982-01-01" @default.
- W1846490335 modified "2023-10-03" @default.
- W1846490335 title "The Regulation of Enzyme Activity by Reversible Phosphorylation" @default.
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- W1846490335 doi "https://doi.org/10.1016/s0079-6123(08)63773-5" @default.
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