FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1846831312> ?p ?o ?g. }

• W1846831312 abstract "The flora of the world contains many plants and fungi with stimulant, hallucinogenic and narcotic effects. For centuries, many of these have been used in initiation rites, physical and spiritual healing and rites of divination. Many of the plants are not placed under any restrictions regarding their use and sale and, with use of the Internet, they are easily obtained. LC-MS/MS and GC-MS methods were developed and used for the detection of 12 plant-derived psychoactive substances, in urine samples, in cases of intoxication. The investigated substances were: asarones, atropine, DMT, ephedrine, harmaline, harmine, ibogaine, LSA, mescaline, psilocin, scopolamine and yohimbine. Urine samples (n=462) from patients admitted to the Maria youth clinic were analyzed for the presence of mescaline. No samples were positive for mescaline, but the method was validated using a clinical sample from a German intoxication case. Urine samples (n=103) from patients admitted to emergency departments all over Sweden were investigated for all 12 substances included in this study. All patients either admitted intake of a psychoactive plant substance or were suspected thereof. In 41 of the 103 samples at least one of the investigated substances was present. The most common substance was psilocin, found in 22 urine samples. Mydriasis, tachycardia, visual hallucinations, nausea and vomiting were the symptoms most often reported. These symptoms can be regarded as minor or moderate in terms of severity. The results suggest a low occurrence of psychoactive plant use in Sweden. Studies were done in attempt to elucidate the metabolic pattern of αand β-asarone in humans. Cis(β)-2,4,5-trimethoxycinnamic acid was regarded to be the most abundant metabolite, evidence of a hydroxylated metabolite, thought to be hydroxylated βasarone, was also found. Today these substances are often marketed on the Internet as “safe” and “legal highs”, which may lead to an increased use and calls for continuous investigation into psychoactive plant intoxications. LIST OF PUBLICATIONS I. Bjornstad K, Helander A, Beck O. Development and Clinical Application of an LC-MS-MS Method for Mescaline in Urine. J Anal Toxicol. 2008;32(3):227-31. II. Bjornstad K, Beck O, Helander A. A multi-component LC-MS/MS method for detection of ten plant-derived psychoactive substances in urine. J Chromatogr B Analyt Technol Biomed Life Sci, 2009; 877(11-12):1162-1168 III. Bjornstad K, Hulten P, Beck O, Helander A. Bioanalytical and clinical evaluation of 103 suspected cases of intoxications with psychoactive plant materials. (Submitted) IV. Bjornstad K, Helander A, Hulten P, Beck O. Bioanalytical Investigation of Asarone in Connection with Acorus calamus Oil Intoxications. (Manuscript) The original articles (I and II) have been printed with permission from the publishers." @default.
• W1846831312 created "2016-06-24" @default.
• W1846831312 creator A5069250665 @default.
• W1846831312 date "2009-05-08" @default.
• W1846831312 modified "2023-09-22" @default.
• W1846831312 title "Mass spectrometric investigation of intoxications with plant-derived psychoactive substances" @default.
• W1846831312 cites W112108890 @default.
• W1846831312 cites W126579187 @default.
• W1846831312 cites W135677869 @default.
• W1846831312 cites W1497404563 @default.
• W1846831312 cites W1497508684 @default.
• W1846831312 cites W1525003375 @default.
• W1846831312 cites W1559919694 @default.
• W1846831312 cites W1561733128 @default.
• W1846831312 cites W157802090 @default.
• W1846831312 cites W1595176569 @default.
• W1846831312 cites W1971124725 @default.
• W1846831312 cites W1972533468 @default.
• W1846831312 cites W1973029389 @default.
• W1846831312 cites W1973316871 @default.
• W1846831312 cites W1977037849 @default.
• W1846831312 cites W1977688928 @default.
• W1846831312 cites W1978216187 @default.
• W1846831312 cites W1983655192 @default.
• W1846831312 cites W1985368040 @default.
• W1846831312 cites W1986929790 @default.
• W1846831312 cites W1988136781 @default.
• W1846831312 cites W1989824060 @default.
• W1846831312 cites W1990408681 @default.
• W1846831312 cites W1991599043 @default.
• W1846831312 cites W1995573137 @default.
• W1846831312 cites W1998147745 @default.
• W1846831312 cites W1999499519 @default.
• W1846831312 cites W2000042675 @default.
• W1846831312 cites W2000983103 @default.
• W1846831312 cites W2013576699 @default.
• W1846831312 cites W2016371428 @default.
• W1846831312 cites W2027817372 @default.
• W1846831312 cites W2027859693 @default.
• W1846831312 cites W2028382512 @default.
• W1846831312 cites W2029651602 @default.
• W1846831312 cites W2042663193 @default.
• W1846831312 cites W2043675566 @default.
• W1846831312 cites W2045988021 @default.
• W1846831312 cites W2051782385 @default.
• W1846831312 cites W2052499997 @default.
• W1846831312 cites W2056232804 @default.
• W1846831312 cites W2059976461 @default.
• W1846831312 cites W2065367797 @default.
• W1846831312 cites W2065829871 @default.
• W1846831312 cites W2074776887 @default.
• W1846831312 cites W2077101160 @default.
• W1846831312 cites W2081883085 @default.
• W1846831312 cites W2085035653 @default.
• W1846831312 cites W2088354687 @default.
• W1846831312 cites W2089922200 @default.
• W1846831312 cites W2096910728 @default.
• W1846831312 cites W2100834951 @default.
• W1846831312 cites W2100962265 @default.
• W1846831312 cites W2104447546 @default.
• W1846831312 cites W2105516408 @default.
• W1846831312 cites W2109134899 @default.
• W1846831312 cites W2110879932 @default.
• W1846831312 cites W2110965473 @default.
• W1846831312 cites W2111452082 @default.
• W1846831312 cites W2113099805 @default.
• W1846831312 cites W2113388885 @default.
• W1846831312 cites W2124026487 @default.
• W1846831312 cites W2125200678 @default.
• W1846831312 cites W2127452552 @default.
• W1846831312 cites W2128128745 @default.
• W1846831312 cites W2136307956 @default.
• W1846831312 cites W2139748231 @default.
• W1846831312 cites W2145384691 @default.
• W1846831312 cites W2150654093 @default.
• W1846831312 cites W2150903999 @default.
• W1846831312 cites W2153528881 @default.
• W1846831312 cites W2156120803 @default.
• W1846831312 cites W2161083324 @default.
• W1846831312 cites W2161617741 @default.
• W1846831312 cites W2163176525 @default.
• W1846831312 cites W2164680276 @default.
• W1846831312 cites W2165571400 @default.
• W1846831312 cites W2228280218 @default.
• W1846831312 cites W2283526650 @default.
• W1846831312 cites W2299878330 @default.
• W1846831312 cites W2911473403 @default.
• W1846831312 cites W3135291502 @default.
• W1846831312 cites W342619094 @default.
• W1846831312 cites W85782555 @default.
• W1846831312 hasPublicationYear "2009" @default.
• W1846831312 type Work @default.
• W1846831312 sameAs 1846831312 @default.
• W1846831312 citedByCount "0" @default.
• W1846831312 crossrefType "dissertation" @default.
• W1846831312 hasAuthorship W1846831312A5069250665 @default.
• W1846831312 hasConcept C124315065 @default.
• W1846831312 hasConcept C126322002 @default.
• W1846831312 hasConcept C144024400 @default.
• W1846831312 hasConcept C170493617 @default.

• next