Matches in SemOpenAlex for { <https://semopenalex.org/work/W1846961001> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1846961001 endingPage "29" @default.
- W1846961001 startingPage "24" @default.
- W1846961001 abstract "Lens regeneration in adult newts is always initiated from the dorsal iris by transdifferentiation of the pigment epithelial cells. One of the most important early events should be the ability of pigment epithelial cells to dedifferentiate and re‐enter the cell cycle. As a first step in an attempt to study this event, we have decided to examine the effects of a cyclin‐dependent kinase‐2 inhibitor on lens regeneration. At the appropriate concentration, this inhibitor completely abolished the ability of pigment epithelial cells to form a new lens, but it did not stop them from dedifferentiating and forming a small lens vesicle. The effects of this inhibitor seem to be mediated by its opposite effects on cell proliferation and apoptosis. The inhibitor significantly reduced cell proliferation and enhanced apoptosis of pigment epithelial cells both in vitro and in vivo and of the regenerating lens in vivo." @default.
- W1846961001 created "2016-06-24" @default.
- W1846961001 creator A5019335002 @default.
- W1846961001 creator A5034790064 @default.
- W1846961001 creator A5057807333 @default.
- W1846961001 creator A5063047638 @default.
- W1846961001 creator A5078274533 @default.
- W1846961001 creator A5088339230 @default.
- W1846961001 date "2004-01-01" @default.
- W1846961001 modified "2023-10-17" @default.
- W1846961001 title "Effects of a CDK inhibitor on lens regeneration" @default.
- W1846961001 cites W1834050293 @default.
- W1846961001 cites W1966407157 @default.
- W1846961001 cites W1981391513 @default.
- W1846961001 cites W1984219920 @default.
- W1846961001 cites W1996931202 @default.
- W1846961001 cites W2025618547 @default.
- W1846961001 cites W2067238416 @default.
- W1846961001 cites W2074947501 @default.
- W1846961001 cites W2078705996 @default.
- W1846961001 cites W2121619780 @default.
- W1846961001 cites W2151575857 @default.
- W1846961001 cites W2159112540 @default.
- W1846961001 cites W2166388925 @default.
- W1846961001 cites W34393502 @default.
- W1846961001 doi "https://doi.org/10.1111/j.1067-1927.2004.012107.x" @default.
- W1846961001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14974961" @default.
- W1846961001 hasPublicationYear "2004" @default.
- W1846961001 type Work @default.
- W1846961001 sameAs 1846961001 @default.
- W1846961001 citedByCount "10" @default.
- W1846961001 countsByYear W18469610012012 @default.
- W1846961001 countsByYear W18469610012014 @default.
- W1846961001 countsByYear W18469610012015 @default.
- W1846961001 countsByYear W18469610012016 @default.
- W1846961001 countsByYear W18469610012020 @default.
- W1846961001 crossrefType "journal-article" @default.
- W1846961001 hasAuthorship W1846961001A5019335002 @default.
- W1846961001 hasAuthorship W1846961001A5034790064 @default.
- W1846961001 hasAuthorship W1846961001A5057807333 @default.
- W1846961001 hasAuthorship W1846961001A5063047638 @default.
- W1846961001 hasAuthorship W1846961001A5078274533 @default.
- W1846961001 hasAuthorship W1846961001A5088339230 @default.
- W1846961001 hasConcept C124320809 @default.
- W1846961001 hasConcept C151730666 @default.
- W1846961001 hasConcept C15336307 @default.
- W1846961001 hasConcept C171056886 @default.
- W1846961001 hasConcept C190283241 @default.
- W1846961001 hasConcept C207001950 @default.
- W1846961001 hasConcept C2778298596 @default.
- W1846961001 hasConcept C28328180 @default.
- W1846961001 hasConcept C29537977 @default.
- W1846961001 hasConcept C54355233 @default.
- W1846961001 hasConcept C55493867 @default.
- W1846961001 hasConcept C60870556 @default.
- W1846961001 hasConcept C86803240 @default.
- W1846961001 hasConcept C95444343 @default.
- W1846961001 hasConceptScore W1846961001C124320809 @default.
- W1846961001 hasConceptScore W1846961001C151730666 @default.
- W1846961001 hasConceptScore W1846961001C15336307 @default.
- W1846961001 hasConceptScore W1846961001C171056886 @default.
- W1846961001 hasConceptScore W1846961001C190283241 @default.
- W1846961001 hasConceptScore W1846961001C207001950 @default.
- W1846961001 hasConceptScore W1846961001C2778298596 @default.
- W1846961001 hasConceptScore W1846961001C28328180 @default.
- W1846961001 hasConceptScore W1846961001C29537977 @default.
- W1846961001 hasConceptScore W1846961001C54355233 @default.
- W1846961001 hasConceptScore W1846961001C55493867 @default.
- W1846961001 hasConceptScore W1846961001C60870556 @default.
- W1846961001 hasConceptScore W1846961001C86803240 @default.
- W1846961001 hasConceptScore W1846961001C95444343 @default.
- W1846961001 hasIssue "1" @default.
- W1846961001 hasLocation W18469610011 @default.
- W1846961001 hasLocation W18469610012 @default.
- W1846961001 hasOpenAccess W1846961001 @default.
- W1846961001 hasPrimaryLocation W18469610011 @default.
- W1846961001 hasRelatedWork W1577076548 @default.
- W1846961001 hasRelatedWork W1824286673 @default.
- W1846961001 hasRelatedWork W1984219920 @default.
- W1846961001 hasRelatedWork W2069053277 @default.
- W1846961001 hasRelatedWork W2398239432 @default.
- W1846961001 hasRelatedWork W2467393879 @default.
- W1846961001 hasRelatedWork W2794059978 @default.
- W1846961001 hasRelatedWork W2984843449 @default.
- W1846961001 hasRelatedWork W4290210633 @default.
- W1846961001 hasRelatedWork W4361813553 @default.
- W1846961001 hasVolume "12" @default.
- W1846961001 isParatext "false" @default.
- W1846961001 isRetracted "false" @default.
- W1846961001 magId "1846961001" @default.
- W1846961001 workType "article" @default.