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- W1847029572 abstract "The present study aimed to assess the relationship between variability in genes related to the pathophysiology of obsessive-compulsive disorder (OCD) and the concentration of different neurometabolites in the anterior cingulate cortex (ACC).We concomitantly assessed neurometabolite concentrations using 3-T (1)H-MRS and 262 single nucleotide polymorphism (SNPs) in 35 genes in 41 paediatric OCD patients.There were significant associations, after Bonferroni correction, between the concentration of inositol, glutamate and glutamine, and total choline and five polymorphisms located in genes related to serotonin and glutamate (i.e., the vesicular monoamine transporter 1 gene, SLC18A1 [rs6586896]; the serotonin receptor 1B gene, HTR1B [rs6296 and rs6298]; and the glutamate receptor, ionotropic, AMPA1 gene, GRIA1 [rs707176 and rs2963944]).The association observed between these polymorphisms and the neurometabolite concentrations could indicate the presence of a biological interaction between the serotonin and the glutamate pathways that could be involved in the pathophysiology of OCD. More studies with this methodology could increase our understanding of the aetiology and pathophysiology of OCD in children." @default.
- W1847029572 created "2016-06-24" @default.
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- W1847029572 date "2015-12-14" @default.
- W1847029572 modified "2023-10-14" @default.
- W1847029572 title "Association between genetic variants of serotonergic and glutamatergic pathways and the concentration of neurometabolites of the anterior cingulate cortex in paediatric patients with obsessive–compulsive disorder" @default.
- W1847029572 cites W1451755597 @default.
- W1847029572 cites W1730237872 @default.
- W1847029572 cites W1854094273 @default.
- W1847029572 cites W190002334 @default.
- W1847029572 cites W1965264828 @default.
- W1847029572 cites W1969645056 @default.
- W1847029572 cites W1977874045 @default.
- W1847029572 cites W1978785291 @default.
- W1847029572 cites W1983302342 @default.
- W1847029572 cites W1984723981 @default.
- W1847029572 cites W1995908911 @default.
- W1847029572 cites W1996838604 @default.
- W1847029572 cites W2000350151 @default.
- W1847029572 cites W2002375162 @default.
- W1847029572 cites W2010479278 @default.
- W1847029572 cites W2011692649 @default.
- W1847029572 cites W2015735421 @default.
- W1847029572 cites W2024341364 @default.
- W1847029572 cites W2024747286 @default.
- W1847029572 cites W2025680458 @default.
- W1847029572 cites W2026834257 @default.
- W1847029572 cites W2036459306 @default.
- W1847029572 cites W2040241585 @default.
- W1847029572 cites W2042309964 @default.
- W1847029572 cites W2042514413 @default.
- W1847029572 cites W2043446004 @default.
- W1847029572 cites W2046334303 @default.
- W1847029572 cites W2049914435 @default.
- W1847029572 cites W2050239239 @default.
- W1847029572 cites W2051607590 @default.
- W1847029572 cites W2052861911 @default.
- W1847029572 cites W2053626793 @default.
- W1847029572 cites W2057120528 @default.
- W1847029572 cites W2058108929 @default.
- W1847029572 cites W2059815221 @default.
- W1847029572 cites W2060368209 @default.
- W1847029572 cites W2062112196 @default.
- W1847029572 cites W2063763633 @default.
- W1847029572 cites W2068955681 @default.
- W1847029572 cites W2073516522 @default.
- W1847029572 cites W2077016065 @default.
- W1847029572 cites W2078695322 @default.
- W1847029572 cites W2079449224 @default.
- W1847029572 cites W2081841619 @default.
- W1847029572 cites W2086123233 @default.
- W1847029572 cites W2088382955 @default.
- W1847029572 cites W2088906118 @default.
- W1847029572 cites W2091918248 @default.
- W1847029572 cites W2092381672 @default.
- W1847029572 cites W2102967434 @default.
- W1847029572 cites W2107177274 @default.
- W1847029572 cites W2110804666 @default.
- W1847029572 cites W2111396411 @default.
- W1847029572 cites W2115693974 @default.
- W1847029572 cites W2116655758 @default.
- W1847029572 cites W2118136004 @default.
- W1847029572 cites W2118328164 @default.
- W1847029572 cites W2121477496 @default.
- W1847029572 cites W2125232095 @default.
- W1847029572 cites W2128250859 @default.
- W1847029572 cites W2130722072 @default.
- W1847029572 cites W2138096904 @default.
- W1847029572 cites W2142016029 @default.
- W1847029572 cites W2143828201 @default.
- W1847029572 cites W2145962041 @default.
- W1847029572 cites W2146283620 @default.
- W1847029572 cites W2148831687 @default.
- W1847029572 cites W2153353641 @default.
- W1847029572 cites W2153611278 @default.
- W1847029572 cites W2155298532 @default.
- W1847029572 cites W2158316668 @default.
- W1847029572 cites W2159109047 @default.
- W1847029572 cites W2161036233 @default.
- W1847029572 cites W4211038581 @default.
- W1847029572 cites W4247665917 @default.
- W1847029572 doi "https://doi.org/10.3109/15622975.2015.1111524" @default.
- W1847029572 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26505676" @default.
- W1847029572 hasPublicationYear "2015" @default.
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