Matches in SemOpenAlex for { <https://semopenalex.org/work/W1847067998> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1847067998 endingPage "170" @default.
- W1847067998 startingPage "159" @default.
- W1847067998 abstract "The primary aim of this study was to compare the efficacy and safety of single-dose fluconazole and a 7-day regimen of itraconazole for the treatment of oropharyngeal candidiasis in human immunodeficiency virus (HIV)-positive patients. In this open-label trial, 40 HIV-positive patients with oropharyngeal candidiasis were randomized to receive either one dose of fluconazole 150 mg or seven daily doses of itraconazole 100 mg. Clinical condition was assessed at baseline, day 8, and day 30 (follow-up). In the fluconazole group, 15 of 20 (75%) patients were clinically cured on day 8, three (15%) were clinically improved, and two (10%) were treatment failures. At follow-up, six (30%) patients experienced relapse. In the itraconazole group, four of 17 (24%) patients were clinically cured at 8 days, and two (12%) were clinically improved; two patients relapsed by day 30. Ten (50%) patients in the itraconazole group were taking concomitant medications that could potentially affect the bioavailability of itraconazole. After excluding the results from these patients, clinical response rates remained significantly higher in the fluconazole treatment arm. These results suggest that a single 150-mg dose of fluconazole may be a safe, effective, and convenient therapy for acquired immune deficiency syndrome-related oropharyngeal candidiasis. The lower response rate in the patients who received itraconazole 100 mg daily for 7 days could be explained by drug interactions and the unpredictable absorption of itraconazole." @default.
- W1847067998 created "2016-06-24" @default.
- W1847067998 creator A5037870737 @default.
- W1847067998 creator A5039795513 @default.
- W1847067998 creator A5042823176 @default.
- W1847067998 creator A5066704334 @default.
- W1847067998 date "1998-06-01" @default.
- W1847067998 modified "2023-09-30" @default.
- W1847067998 title "Safety and Efficacy of Single-Dose Fluconazole Compared with a 7-Day Regimen of Itraconazole in the Treatment of AIDS-Related Oropharyngeal Candidiasis" @default.
- W1847067998 cites W1178514020 @default.
- W1847067998 cites W1970631373 @default.
- W1847067998 cites W1974126157 @default.
- W1847067998 cites W1978615086 @default.
- W1847067998 cites W1981516536 @default.
- W1847067998 cites W1984513537 @default.
- W1847067998 cites W2002155710 @default.
- W1847067998 cites W2012066169 @default.
- W1847067998 cites W2019835459 @default.
- W1847067998 cites W2033154566 @default.
- W1847067998 cites W2056863521 @default.
- W1847067998 cites W2077462547 @default.
- W1847067998 cites W2083630487 @default.
- W1847067998 cites W2085259535 @default.
- W1847067998 cites W2088006342 @default.
- W1847067998 cites W2138866540 @default.
- W1847067998 cites W2140389942 @default.
- W1847067998 cites W2158267732 @default.
- W1847067998 cites W2160539237 @default.
- W1847067998 cites W2170512364 @default.
- W1847067998 cites W2320476004 @default.
- W1847067998 cites W2324725162 @default.
- W1847067998 cites W2985663742 @default.
- W1847067998 doi "https://doi.org/10.1177/030006059802600307" @default.
- W1847067998 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9718471" @default.
- W1847067998 hasPublicationYear "1998" @default.
- W1847067998 type Work @default.
- W1847067998 sameAs 1847067998 @default.
- W1847067998 citedByCount "13" @default.
- W1847067998 countsByYear W18470679982012 @default.
- W1847067998 countsByYear W18470679982016 @default.
- W1847067998 countsByYear W18470679982021 @default.
- W1847067998 crossrefType "journal-article" @default.
- W1847067998 hasAuthorship W1847067998A5037870737 @default.
- W1847067998 hasAuthorship W1847067998A5039795513 @default.
- W1847067998 hasAuthorship W1847067998A5042823176 @default.
- W1847067998 hasAuthorship W1847067998A5066704334 @default.
- W1847067998 hasConcept C126322002 @default.
- W1847067998 hasConcept C16005928 @default.
- W1847067998 hasConcept C2777071850 @default.
- W1847067998 hasConcept C2779384505 @default.
- W1847067998 hasConcept C2779548794 @default.
- W1847067998 hasConcept C2780315139 @default.
- W1847067998 hasConcept C2780651595 @default.
- W1847067998 hasConcept C2781413609 @default.
- W1847067998 hasConcept C535046627 @default.
- W1847067998 hasConcept C71924100 @default.
- W1847067998 hasConcept C90924648 @default.
- W1847067998 hasConceptScore W1847067998C126322002 @default.
- W1847067998 hasConceptScore W1847067998C16005928 @default.
- W1847067998 hasConceptScore W1847067998C2777071850 @default.
- W1847067998 hasConceptScore W1847067998C2779384505 @default.
- W1847067998 hasConceptScore W1847067998C2779548794 @default.
- W1847067998 hasConceptScore W1847067998C2780315139 @default.
- W1847067998 hasConceptScore W1847067998C2780651595 @default.
- W1847067998 hasConceptScore W1847067998C2781413609 @default.
- W1847067998 hasConceptScore W1847067998C535046627 @default.
- W1847067998 hasConceptScore W1847067998C71924100 @default.
- W1847067998 hasConceptScore W1847067998C90924648 @default.
- W1847067998 hasIssue "3" @default.
- W1847067998 hasLocation W18470679981 @default.
- W1847067998 hasLocation W18470679982 @default.
- W1847067998 hasOpenAccess W1847067998 @default.
- W1847067998 hasPrimaryLocation W18470679981 @default.
- W1847067998 hasRelatedWork W1847067998 @default.
- W1847067998 hasRelatedWork W1916615072 @default.
- W1847067998 hasRelatedWork W1981223517 @default.
- W1847067998 hasRelatedWork W2046034819 @default.
- W1847067998 hasRelatedWork W2061770781 @default.
- W1847067998 hasRelatedWork W2088063431 @default.
- W1847067998 hasRelatedWork W2136366292 @default.
- W1847067998 hasRelatedWork W3208778405 @default.
- W1847067998 hasRelatedWork W4315796140 @default.
- W1847067998 hasRelatedWork W4322626821 @default.
- W1847067998 hasVolume "26" @default.
- W1847067998 isParatext "false" @default.
- W1847067998 isRetracted "false" @default.
- W1847067998 magId "1847067998" @default.
- W1847067998 workType "article" @default.